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Uncategorized Published - 15 December, 2016    By - Dr Clemens
Response Patterns to the Electric Stimulation of Epidural Catheters in Pregnant Women: A Randomized Controlled Trial of Uniport Versus Multiport Catheters

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 950–954 AUTHORS: Patel, Ruchira MBBS et al BACKGROUND: The transcatheter electric stimulation test (Tsui test) can be performed at the bedside to confirm the correct placement of a wire-reinforced epidural catheter within the epidural space. The most commonly observed motor response with […]

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Uncategorized Published - 15 December, 2016    By - Dr Clemens
Prevention of Spinal Anesthesia-Induced Hypotension During Cesarean Delivery by 5-Hydroxytryptamine-3 Receptor Antagonists: A Systematic Review and Meta-analysis and Meta-regression

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 977–988 AUTHORS: Heesen, Michael MD, PhD et al BACKGROUND: Hypotension remains a frequent complication of spinal anesthesia, increasing the risk of nausea and vomiting, altered mental status, and aspiration. The aim of this systematic review and meta-analysis was to determine whether 5-hydroxytryptamine3 […]

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Uncategorized Published - 15 December, 2016    By - Dr Clemens
Implementation of Programmed Intermittent Epidural Bolus for the Maintenance of Labor Analgesia

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 965–971 AUTHORS: Carvalho, Brendan MBBCh, FRCA, MDCH et al Programmed intermittent epidural bolus (PIEB) is an exciting new technology that has the potential to improve the maintenance of epidural labor analgesia. PIEB compared with a continuous epidural infusion (CEI) has the potential […]

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Uncategorized Published - 14 December, 2016    By - Dr Clemens
The Amount of Fluid Given During Surgery That Leaks Into the Interstitium Correlates With Infused Fluid Volume and Varies Widely Between Patients

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 925–932 AUTHORS: Nishimura, Akiko DDS, PhD et al BACKGROUND: The revised Starling law suggests that intravenously infused fluid may leak into the interstitium and not remain in the intravascular space. This hypothesis is supported by clinical findings that postoperative weight gain is […]

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Uncategorized Published - 14 December, 2016    By - Dr Clemens
Impact of an Analgesia-Based Sedation Protocol on Mechanically Ventilated Patients in a Medical Intensive Care Unit

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 903–909 AUTHORS: Faust, Andrew C. PharmD, BCPS et al BACKGROUND: Recent attention to adverse effects of intensive care unit (ICU) sedation has led to the use of strategies that target a “lighter” depth of sedation. Among these strategies are “analgosedation” protocols, which […]

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Uncategorized Published - 14 December, 2016    By - Dr Clemens
The Feasibility of a Completely Automated Total IV Anesthesia Drug Delivery System for Cardiac Surgery

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 885–893 AUTHORS: Zaouter, Cedrick MD, MSc et al BACKGROUND: In this pilot study, we tested a novel automatic anesthesia system for closed-loop administration of IV anesthesia drugs for cardiac surgical procedures with cardiopulmonary bypass. This anesthesia drug delivery robot integrates all 3 […]

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Uncategorized Published - 14 December, 2016    By - Dr Clemens
Effect of Intraoperative Glucose Infusion on Catabolism of Adipose Tissue and Muscle Protein in Patients Anesthetized With Remifentanil in Combination With Sevoflurane During Major Surgery: A Randomized Controlled Multicenter Trial

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 869–876 AUTHORS: Sawada, Atsushi MD, PhD et al BACKGROUND: A harmful effect of stress hormone secretion during surgery is lipolysis and proteolysis to maintain normal blood glucose levels. A well-titrated general anesthetic improves blood glucose control by suppressing secretion of these stress […]

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Uncategorized Published - 14 December, 2016    By - Dr Clemens
Targeted Coagulation Management in Severe Trauma: The Controversies and the Evidence

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 910–924 AUTHORS: Winearls, James BSc, MBBS, MRCP, FCICM et al Hemorrhage in the setting of severe trauma is a leading cause of death worldwide. The pathophysiology of hemorrhage and coagulopathy in severe trauma is complex and remains poorly understood. Most clinicians currently […]

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Uncategorized Published - 13 December, 2016    By - Dr Clemens
The Impact of Residual Neuromuscular Blockade, Oversedation, and Hypothermia on Adverse Respiratory Events in a Postanesthetic Care Unit: A Prospective Study of Prevalence, Predictors, and Outcomes

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 859–868 AUTHORS: Stewart, Paul A. MBBS, FANZCA et al BACKGROUND: Residual neuromuscular blockade (RNMB) has been linked to adverse respiratory events (AREs) in the postanesthetic care unit (PACU). However, these events are often not attributed to RNMB by anesthesiologists because they may […]

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Uncategorized Published - 13 December, 2016    By - Dr Clemens
Does Propofol Anesthesia Lead to Less Postoperative Pain Compared With Inhalational Anesthesia?: A Systematic Review and Meta-analysis

Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 846–858 AUTHORS: Peng, Ke MS et al BACKGROUND: Many studies have compared propofol-based anesthesia with inhalational anesthesia. Results from several studies have shown improved postoperative analgesia after propofol anesthesia, but other studies showed contradictory results. There are no large prospective studies that […]

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