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Anesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 885–893 AUTHORS: Zaouter, Cedrick MD, MSc et al BACKGROUND: In this pilot study, we tested a novel automatic anesthesia system for closed-loop administration of IV anesthesia drugs for cardiac surgical procedures with cardiopulmonary bypass. This anesthesia drug delivery robot integrates all 3 […]
Read MoreAnesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 869–876 AUTHORS: Sawada, Atsushi MD, PhD et al BACKGROUND: A harmful effect of stress hormone secretion during surgery is lipolysis and proteolysis to maintain normal blood glucose levels. A well-titrated general anesthetic improves blood glucose control by suppressing secretion of these stress […]
Read MoreAnesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 910–924 AUTHORS: Winearls, James BSc, MBBS, MRCP, FCICM et al Hemorrhage in the setting of severe trauma is a leading cause of death worldwide. The pathophysiology of hemorrhage and coagulopathy in severe trauma is complex and remains poorly understood. Most clinicians currently […]
Read MoreAnesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 859–868 AUTHORS: Stewart, Paul A. MBBS, FANZCA et al BACKGROUND: Residual neuromuscular blockade (RNMB) has been linked to adverse respiratory events (AREs) in the postanesthetic care unit (PACU). However, these events are often not attributed to RNMB by anesthesiologists because they may […]
Read MoreAnesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 846–858 AUTHORS: Peng, Ke MS et al BACKGROUND: Many studies have compared propofol-based anesthesia with inhalational anesthesia. Results from several studies have shown improved postoperative analgesia after propofol anesthesia, but other studies showed contradictory results. There are no large prospective studies that […]
Read MoreAnesthesia & Analgesia: October 2016 – Volume 123 – Issue 4 – p 824–830 AUTHORS: Faraoni, David MD, PhD et al BACKGROUND: Children with major and severe congenital heart disease (CHD) undergoing noncardiac surgery are at increased risk of mortality. The objective of this study was to identify the predictors for in-hospital mortality, and to […]
Read MoreAnesthesia & Analgesia: December 2016 – Volume 123 – Issue 6 – p 1408–1415 AUTHORS: Staalsø, Jonatan Myrup MD, PhD et al BACKGROUND: Gly16arg polymorphism of the adrenergic β2-receptor is associated with the elevated cardiac output (Q) in healthy gly16-homozygotic subjects. We questioned whether this polymorphism also affects Q and regional cerebral oxygen saturation (SCO2) during anesthesia in […]
Read MoreOne-third of American adults are obese. Due diligence and proper screening are the keys to preventing problems. While difficult airways are common in obese patients, BMI shouldn’t be the lone determining factor when deciding whether to treat them. There are other considerations which are just as important including a patient’s Mallampati score and neck circumference. […]
Read MoreAnesthesia & Analgesia: November 2016 – Volume 123 – Issue 5 – p 1158–1162 AUTHORS: Dayan, Amir C. MD et al BACKGROUND: An intact pilot balloon assembly is crucial to the proper function of a cuffed tracheal tube. Disruption of the pilot balloon, transection of the inflation line, or valve incompetence results in cuff deflation, […]
Read MoreAnesthesia & Analgesia: December 2016 – Volume 123 – Issue 6 – p 1480–1489 AUTHORS: Oprea, Adriana D. MD et al BACKGROUND: Increased pulse pressure (PP) is an important independent predictor of cardiovascular outcome and acute kidney injury (AKI) after cardiac surgery. The objective of this study was to determine whether elevated baseline PP is […]
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