Authors: Nasr VG et al. Journal: Anesthesiology, December 9, 2025. DOI: 10.1097/ALN.0000000000005783 SummaryThis large multicenter registry study evaluated the incidence and risk factors for intraoperative cardiac events in pediatric patients with congenital heart disease (CHD) undergoing noncardiac procedures. Unlike prior studies limited to mortality outcomes or single-center experiences, this analysis provides granular, contemporary data on […]
Read MoreAuthors: Jansen S et al. Journal: Anesthesiology, December 11, 2025. DOI: 10.1097/ALN.0000000000005894 SummaryThis randomized, double-blind, placebo-controlled crossover study compared the respiratory and analgesic effects of cebranopadol—a dual nociceptin (NOP) and mu-opioid (MOP) receptor agonist—with those of the full MOP agonist oxycodone in healthy volunteers. Given ongoing concerns about opioid-induced respiratory depression, the investigators sought to […]
Read MoreAuthor: Sophie Eydis Becker’s ASC Review Anesthesiology is heading into a pivotal year, as workforce volatility, reimbursement pressure and policy shifts collide with rising surgical demand and expanding outpatient care. After a period of partial stabilization, leaders say the structural forces reshaping how anesthesia is staffed, paid and deployed are intensifying, with direct implications for hospitals, […]
Read MoreAuthors: Persson NDA et al. Journal: Anesthesiology, December 12, 2025. DOI: 10.1097/ALN.0000000000005794 SummaryThis preclinical imaging study examined how general anesthetic technique and systemic hyperosmolality influence the distribution of intrathecally administered drugs delivered at the lumbar level. Because lumbar intrathecal drug delivery often fails to achieve therapeutic intracranial concentrations, the investigators explored whether anesthetic choice and […]
Read MoreAuthors: Zelber-Sagi S et al. Journal: Anesthesiology, December 12, 2025. DOI: 10.1097/ALN.0000000000005830 SummaryThis large multicenter retrospective analysis evaluated whether the Fibrosis-4 (FIB-4) score—an inexpensive, routinely available marker of liver fibrosis—is associated with perioperative mortality and complications in patients undergoing general anesthesia who did not have clinically apparent liver disease. Given the high prevalence of metabolic […]
Read MoreAuthors: Padilla A et al. Journal: Anesthesiology, December 16, 2025. DOI: 10.1097/ALN.0000000000005788 SummaryThis multicenter retrospective cohort study examined contemporary anesthetic practice patterns for cesarean hysterectomy in patients with placenta accreta spectrum across U.S. hospitals. Using the Multicenter Perioperative Outcomes Group database, the investigators sought to characterize modes of anesthesia and identify clinical factors associated with […]
Read MoreAuthors: Tong C et al. Journal: Anesthesiology, December 29, 2025. DOI: 10.1097/ALN.0000000000005846 SummaryThis randomized controlled trial evaluated the analgesic efficacy and safety of an ultrasound-guided external oblique intercostal (EOI) plane block with ropivacaine in patients undergoing elective open hepatectomy. The study addressed an important clinical gap for patients in whom epidural or paravertebral analgesia may […]
Read MoreAuthor: Patsy Newitt Becker’s ASC Review As physician employment accelerates, anesthesia leaders say the biggest pressure points are structural rather than clinical. Anesthesiologist Jason Hennes, MD, founder of anesthesia data and scheduling platform Anesthesia Data Services, joined Becker’s to discuss the workforce trends shaping how groups staff, pay and measure productivity. Editor’s note: This interview was edited lightly for clarity and […]
Read MoreAuthors: Hovgaard HL et al. Journal: Anesthesiology, Accepted December 26, 2025. DOI: 10.1097/ALN.0000000000005919 SummaryThis prospective, single-blind randomized controlled trial evaluated whether extending goal-directed fluid therapy (GDFT) into the postoperative period using individualized blood pressure targets improves outcomes after oesophagectomy. Given the high morbidity associated with oesophagectomy and the limitations of traditional GDFT—particularly fixed mean arterial […]
Read MoreAuthors: Donovan AL et al. Journal: Anesthesiology, Accepted December 26, 2025. DOI: 10.1097/ALN.0000000000005920 SummaryThis qualitative focus group study explored how anesthesiologists in academic practice define career fulfillment and navigate competing clinical, academic, and personal demands across different career stages. Given that anesthesiologists report the highest intent to leave academic medicine among medical specialties, the authors […]
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