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Uncategorized Published - 24 January, 2023    By - Dr Clemens
Chemotherapy-Induced Peripheral Neuropathy Treatments

Authors: Aranke M et al Pract Pain Manag. 2023 January/February;23(1). Introduction Chemotherapy-induced peripheral neuropathy (CIPN) affects between 40% and 70% of individuals undergoing chemotherapy and may significantly affect quality of life by worsening symptomatic clusters, such as psychological distress, fatigue-related pain, and abdominal discomfort.¹˒² There are several proposed mechanisms for CIPN. These range from the […]

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Uncategorized Published - 23 January, 2023    By - Dr Clemens
Selection Bias in the Hypotension Prediction Index: Comment

Author: Enrico Giustiniano, M.D.; Fulvio Nisi, M.D. Anesthesiology January 2023. To the Editor: We read with interest the article by Enevoldsen and Vistisen about the predictive model of intraoperative hypotension.  Regarding the criticism the authors made about what they named “gray-zone outcome,” we would like to provide some comments. The Hypotension Prediction Index is a new parameter […]

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Uncategorized Published - 23 January, 2023    By - Dr Clemens
Selection Bias in the Hypotension Prediction Index: Reply

Autors: Johannes Enevoldsen, M.D. et al  Anesthesiology January 2023. In Reply: We have read the interesting comment by Giustiniano and Nisi  about our article.  The authors highlight that the diastolic arterial blood pressure can decrease significantly when the Hypotension Prediction Index (hereafter the Index) reaches approximately 50 and argue for the possible need for treatment when diastolic arterial […]

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Uncategorized Published - 23 January, 2023    By - Dr Clemens
Immediate hypersensitivity to chlorhexidine: experience from an allergy centre in China

Authors: Hao Xiao, M.S. et al Anesthesiology January 2023. Background Chlorhexidine generally has a good safety profile. However, allergic reactions are reported with increasing frequency. In China, it is rarely reported, and its characteristics are unknown. The purpose of this study was to summarize the experience of a Chinese allergy centre with chlorhexidine allergy. Methods […]

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Uncategorized Published - 23 January, 2023    By - Dr Clemens
Middle Ear Condition at the Time of Pediatric Myringotomy Tube Placement: Pain Associations Following Intraoperative Fentanyl/Ketorolac and Seasonal Variation

AUTHORS: Cohen, William G. BA et al  Anesthesia & Analgesia November 02, 2022. BACKGROUND: Ketorolac-refractory pain behavior following bilateral myringotomy and pressure equalization tube placement (BMT) is associated with the absence of middle ear fluid. Intraoperative fentanyl/ketorolac affords more reliable pain control than ketorolac alone. We hypothesized that middle ear condition would correlate with postoperative […]

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