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AUTHORS: Yang, Zhengbo MD et al Anesthesia & Analgesia: June 21, 2022 BACKGROUND: Sevoflurane (SEVO) increases neuronal excitation in neonatal rodent brains through alteration of gamma aminobutyric acid (GABA)(A) receptor signaling and increases corticosterone release. These actions may contribute to mechanisms that initiate the anesthetic’s long-term neuroendocrine and neurobehavioral effects. Dexmedetomidine (DEX), a non-GABAergic α2-adrenergic receptor […]
Read MoreAUTHORS: Asingei, Juventine MPH et al Anesthesia & Analgesia: June 22, 2022 BACKGROUND: The populations of the East, Central, and Southern African regions receive only a fraction of the surgical procedures they require, and patients are more likely to die after surgery than the global average. An insufficient anesthetic workforce is a key barrier to safe […]
Read MoreDG News Spinal anaesthesia was associated with more pain in the first 24 hours after hip fracture surgery and more prescription analgesic use at 60 days compared with general anaesthesia, according to a study published in the Annals of Internal Medicine. “In our study, patients who got spinal anaesthesia did get fewer opioids in the operating […]
Read MoreAuthor: Beth Sisson MedicalNewsToday Cayenne contains a compound called capsaicin, which may help to relieve pain. Topical application of capsaicin may help to relieve shingles pain. Capsaicin is the compound in cayenne that gives it its spicy flavor and burning sensation. Capsaicin has pain-relieving properties that may help to reduce shingles pain. This article examines […]
Read MoreDG Journal Club AUTHORS: Alessandra Alciati, Fabiola Atzeni, Fausto Salaffi, Piercarlo Sarzi-Puttini Clin Exp Rheumatol. 2022 Jun 13 OBJECTIVES Fibromyalgia (FM) is a syndrome of unknown aetiology characterised by chronic widespread musculoskeletal pain and associated with high rates of psychiatric comorbidities, mainly mood and anxiety disorders.This study aims to determine the age at onset (AAO) […]
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