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Uncategorized Published - 16 February, 2023    By - Dr Clemens
Modulation of Cerebral Function by Muscle Afferent Activity, with Reference to Intravenous Succinylcholine

Author: William L. Lanier, M.D. Anesthesiology February 2023, Vol. 138, 209–215. Cerebral Function and Muscle Afferent Activity Following Intravenous Succinylcholine in Dogs Anesthetized with Halothane: The Effects of Pretreatment with a Defasciculating Dose of Pancuronium. By WL Lanier, PA Iaizzo, and JH Milde. Anesthesiology 1989; 71:87–95. Reprinted with permission.By the mid-1980s, it was widely assumed that if […]

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Uncategorized Published - 15 February, 2023    By - Dr Clemens
ffect of 5% EMLA Cream on Postoperative Sore Throat in Adults Following General Endotracheal Anesthesia

AUTHORS: Murugaiyan, Abishek MD et al  Anesthesia & Analgesia 136(2):p 338-345, February 2023. BACKGROUND: Postoperative sore throat (POST) is a distressing complaint in adults after endotracheal intubation. This study aimed to evaluate the effect of topical application of a eutectic mixture of local anesthetics (EMLA) cream over the endotracheal tube (ETT) cuff on the incidence and […]

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Uncategorized Published - 15 February, 2023    By - Dr Clemens
Dopamine-Antagonist Antiemetics in PONV Management: Entering a New Era?

Authors: Connie Chung, MD; Joseph W. Szokol, MD, JD, MBA Anesthesia Patient Safety Foundation Volume 38, No. 1 • February 2023  INTRODUCTION In the second half of the last century, dopamine D2-receptor antagonists were a mainstay of the management of post-operative nausea and vomiting (PONV).1 However, at the start of the 21st century, they sharply declined in […]

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Uncategorized Published - 15 February, 2023    By - Dr Clemens
Mechanical Power Ratio and Respiratory Treatment Escalation in COVID-19 Pneumonia

Authors: Simone Gattarello, M.D., Ph.D. et al  Anesthesiology March 2023, Vol. 138, 289–298. Background Under the hypothesis that mechanical power ratio could identify the spontaneously breathing patients with a higher risk of respiratory failure, this study assessed lung mechanics in nonintubated patients with COVID-19 pneumonia, aiming to (1) describe their characteristics; (2) compare lung mechanics between […]

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Uncategorized Published - 15 February, 2023    By - Dr Clemens
GABAergic Signaling During Spinal Cord Stimulation Reduces Cardiac Arrhythmias in a Porcine Model

Authors: Kimberly Howard-Quijano, M.D., M.S. et al  Anesthesiology January 2023. Background Neuraxial modulation, including spinal cord stimulation, reduces cardiac sympathoexcitation and ventricular arrhythmogenesis. There is an incomplete understanding of the molecular mechanisms through which spinal cord stimulation modulates cardiospinal neural pathways. We hypothesize that spinal cord stimulation reduces myocardial ischemia/reperfusion induced sympathetic excitation and ventricular […]

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