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Uncategorized Published - 13 April, 2023    By - Dr Clemens
GABAergic Signaling during Spinal Cord Stimulation Reduces Cardiac Arrhythmias in a Porcine Model

Authors: Kimberly Howard-Quijano, M.D., M.S. et al  Anesthesiology April 2023, Vol. 138, 372–387. Background Neuraxial modulation, including spinal cord stimulation, reduces cardiac sympathoexcitation and ventricular arrhythmogenesis. There is an incomplete understanding of the molecular mechanisms through which spinal cord stimulation modulates cardiospinal neural pathways. The authors hypothesize that spinal cord stimulation reduces myocardial ischemia–reperfusion—induced sympathetic excitation […]

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Uncategorized Published - 13 April, 2023    By - Dr Clemens
Human Factors And Peri-operative Care 2023

Authors: Mike Charlesworth and Andrew Klein #TheanesthesiaBlog April 2023 This month, we are delighted to publish a narrative review and guideline on human factors in anaesthesia. The guideline recently received > 11k downloads after being shared widely by Martin Bromiley and holds an Altmetric score of > 200, having been tweeted by 250 users and reported by two news […]

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Uncategorized Published - 13 April, 2023    By - Dr Clemens
The Illicit Drug Market: A Clinical Primer 2023

Author: Bettinger J. Pract Pain Manag. 2023 March/April;23(2). From novel synthetic opioids to psychedelics and cocaine, a guide to today’s illicit substance market, including the underlying mechanisms and physiologic effects that can lead to severe interactions and interrupt care. Polysubstance and Illicit Substance Use Continue to Rise Drug-related overdose deaths have continued to climb over […]

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Uncategorized Published - 13 April, 2023    By - Dr Clemens
Buprenorphine Pain Patch and Side Effect Management 2023

Author: Amarquaye W. Pract Pain Manag. 2023 March/April;23(2). When a patient asks about side effects from his medication patch, clinical hospital pharmacist William Amarquaye advises on proper placement and skin care. Buprenorphine patch helps with back pain, but rash and blistering develop The Patient A patient called our specialty pharmacy inquiring about side effects from […]

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Uncategorized Published - 12 April, 2023    By - Dr Clemens
Motor Vehicle Crash Risk among Adults Undergoing General Surgery 2023

Authors: Timothy G. Gaulton, M.D., M.Sc. et al  Anesthesiology April 2023. Background Surgery causes transient impairment in cognition and function, which may impact driving safety. The authors hypothesized that the risk of a motor vehicle crash would increase after compared to before surgery. Methods The authors performed a nested case-crossover study within population-based observational data […]

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