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Anesthesiology Published - 14 January, 2026    By - Dr Clemens
Efficacy and Safety of Preemptive Magnesium Sulfate Infusion during Pheochromocytoma and Paraganglioma Resection

Authors: Kong H et al. Journal: Anesthesiology, November 25, 2025. DOI: 10.1097/ALN.0000000000005778 SummaryThis randomized, double-blind, placebo-controlled trial evaluated whether preemptive magnesium sulfate infusion improves intraoperative hemodynamic stability during pheochromocytoma and paraganglioma (PPGL) resection—procedures well known for extreme catecholamine-mediated blood pressure and heart rate fluctuations. Ninety-two patients scheduled for PPGL resection were randomized to receive either […]

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Anesthesiology Published - 14 January, 2026    By - Dr Clemens
The anesthesia breakthroughs that defined 2025

Author: Sophie Eydis Becker’s ASC Review Anesthesiology saw a year of significant innovation in 2025 as new technologies, techniques and care models redefined what is possible in the perioperative environment. From AI-driven automation to next-generation pain control, five breakthroughs in particular helped shape the specialty. 1. AI-driven decision support, smart ultrasound and virtual reality-enhanced training […]

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Anesthesiology Published - 13 January, 2026    By - Dr Clemens
Cardiac Biomarkers and Risk Stratification in Liver Transplantation for Acute-on-chronic Liver Failure: Refining Current Risk Models for Improved Prediction of Posttransplant Mortality

Authors: Kwon H-M et al. Journal: Anesthesiology, December 2, 2025. DOI: 10.1097/ALN.0000000000005747 SummaryThis retrospective registry-based study evaluated whether incorporating cardiac biomarkers into existing risk models improves prediction of post–liver transplant mortality in patients with acute-on-chronic liver failure (ACLF). Cardiovascular complications are the leading cause of death after liver transplantation in this population, yet commonly used […]

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Anesthesiology Published - 13 January, 2026    By - Dr Clemens
Liposomal Bupivacaine, Plain Bupivacaine, and Saline for Transversus Abdominis Plane Blocks

Authors: Turan A et al. Journal: Anesthesiology, December 1, 2025. DOI: 10.1097/ALN.0000000000005869 SummaryThis multicenter randomized controlled trial (the CLEVELAND Trial) evaluated whether liposomal bupivacaine provides superior or prolonged analgesia compared with plain bupivacaine or saline when used in single-injection, four-quadrant transversus abdominis plane (TAP) blocks for major abdominal surgery. Given widespread use of liposomal bupivacaine […]

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Anesthesiology Published - 13 January, 2026    By - Dr Clemens
Evaluating The Statistical Robustness Of Randomized Controlled Trials Of Spinal Cord Stimulation For Pain Through The Use Of Fragility Index

Authors: Hussain N et al. Journal: Anesthesiology, December 1, 2025. DOI: 10.1097/ALN.0000000000005876 SummaryThis systematic review evaluated the statistical robustness of randomized controlled trials assessing spinal cord stimulation (SCS for chronic pain using the fragility index (FI). While SCS has gained wide adoption based on statistically significant trial outcomes, the fragility index provides a complementary lens […]

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