⭐ Recognized by FeedSpot: #12 Best Anesthesiology Blog Worldwide

Anesthesiology Published - 7 April, 2026    By - Dr Clemens
Frontal Electroencephalogram Phase–Amplitude Coupling Reflects Nociception and the Analgesic Effect of Transversus Abdominis Plane Block in Laparoscopic Surgery

Authors: Wang T et al. Anesthesiology 144(4):837–852, April 2026 Summary:This prospective study explores whether electroencephalogram (EEG) patterns—specifically phase–amplitude coupling (PAC)—can serve as a real-time marker of nociception and analgesic effectiveness during surgery. Traditional intraoperative monitoring of pain relies largely on indirect signs such as hemodynamics, but EEG-based measures may offer a more direct window into […]

Read More
Anesthesiology Published - 7 April, 2026    By - Dr Clemens
Frequency and Management of Maternal Peripartum Cardiac Arrest during Anesthetic Care

Authors: Furdyna M et al. Anesthesiology 144(4):796–810, April 2026 Summary:This large multicenter retrospective cohort study provides one of the most comprehensive evaluations of maternal cardiac arrest during peripartum anesthetic care in the United States. Using data from over 778,000 deliveries across 60 institutions, the authors identified 87 cases of maternal cardiac arrest, corresponding to an […]

Read More
Anesthesiology Published - 7 April, 2026    By - Dr Clemens
Evaluating the Statistical Robustness of Randomized Controlled Trials of Spinal Cord Stimulation for Pain through the Use of Fragility Index

Authors: Hussain N et al. Anesthesiology 144(4):898–912, April 2026 Summary:This study evaluates the strength of evidence supporting spinal cord stimulation (SCS) for chronic pain by applying the fragility index—a statistical measure that assesses how many outcome changes would be needed to overturn a trial’s results. Unlike traditional P values, the fragility index provides insight into […]

Read More
Anesthesiology Published - 7 April, 2026    By - Dr Clemens
Effects of Isoflurane Inhibition of Mitochondrial Complex I on Calcium Removal in Mouse Neuronal Cultures

Authors: Jung S et al. Anesthesiology 144(4):871–885, April 2026 Summary:This experimental study investigates a key mechanism behind anesthetic-induced neurotoxicity, focusing on how Isoflurane disrupts calcium regulation in neurons. The authors specifically examined whether impaired calcium removal—rather than increased calcium entry—drives neuronal injury. Using mouse neuronal cultures, the study demonstrated that isoflurane significantly prolongs the time […]

Read More
Anesthesiology Published - 7 April, 2026    By - Dr Clemens
Role of Dorsomedial Periaqueductal Gray Glutamatergic Neurons in Promoting Arousal under Multiple General Anesthetics in Mice

Authors: Tong L et al. Anesthesiology 144(4):853–870, April 2026 Summary:This mechanistic study investigates the role of glutamatergic neurons in the dorsomedial periaqueductal gray (dmPAG) as a potential common neural pathway regulating anesthesia and emergence. The periaqueductal gray has long been recognized for its role in pain and defensive behaviors, but its contribution to anesthesia–arousal transitions […]

Read More