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Uncategorized Published - 5 January, 2024    By - Dr Clemens
User-Centered Design of a Machine Learning Dashboard for Prediction of Postoperative Complications

AUTHORS: Fritz, Bradley A. MD, MSCI et al   Anesthesia & Analgesia June 2023.  BACKGROUND: Machine learning models can help anesthesiology clinicians assess patients and make clinical and operational decisions, but well-designed human-computer interfaces are necessary for machine learning model predictions to result in clinician actions that help patients. Therefore, the goal of this study […]

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Uncategorized Published - 5 January, 2024    By - Dr Clemens
Definition of Monitored Anesthesia Care

Authors: Dinesh Ramaiah MBBS et al  O THE EDITOR We appreciate the reprinting in the APSF Newsletter of the article from Anesthesia & Analgesia, (June 2022 • Volume 134 • Number 6, pages 1192–1200), entitled “Pro-Con Debate: Monitored Anesthesia Care Versus General Endotracheal Anesthesia for Endoscopic Retrograde Cholangiopancreatography” by Janik et al., and we hope that in reprinting […]

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Uncategorized Published - 5 January, 2024    By - Dr Clemens
Updates from the Multi-center Handoff Collaborative

Authors: Aalok V. Agarwala, MD, MBA et al  The transition of responsibility and accountability for patient care from one clinical team to another is a routine part of modern health care delivery. Whether between physical locations (e.g., from the emergency department to an inpatient floor), or between teams in a static location (e.g., from a […]

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Uncategorized Published - 5 January, 2024    By - Dr Clemens
Opioid Induced Respiratory Depression— Beyond Sleep Disordered Breathing

Author: Toby N. Weingarten, MD Anesthesia Patient Safety Foundation Volume 38, No. 2 • June 2023  More than a decade ago the APSF established a clear edict: “No patient should be harmed by opioid-induced respiratory depression in the postoperative period.”1 Research studies established a strong association between obstructive sleep apnea (OSA) and adverse postoperative opioid-related outcomes. In […]

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Uncategorized Published - 5 January, 2024    By - Dr Clemens
A Pharmacological Evaluation of the Analgesic Effect and Hippocampal Protein Modulation of the Ketamine Metabolite (2R,6R)-Hydroxynorketamine in Murine Pain Models

AUTHORS: Das, Vaskar PhD et al  Anesthesia & Analgesia June 2023. BACKGROUND: The ketamine metabolite (2R,6R)-hydroxynorketamine ([2R,6R]-HNK) has analgesic efficacy in murine models of acute, neuropathic, and chronic pain. The purpose of this study was to evaluate the α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate (AMPA) dependence of (2R,6R)-HNK analgesia and protein changes in the hippocampus in murine pain models administered […]

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