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Uncategorized Published - 20 June, 2024    By - Dr Clemens
Preoperative Transfusion and Sickle Cell Disease in the Pediatric Patient

Authors: Rahul Baijal, MD; Priti Dalal, MD; Megha Kanjia, MD Anesthesia Patient Safety Foundation June 2024 Volume 39, No. 2  SUMMARY:Perioperative complications are more common in patients with SCD compared to the general population with an increased risk of postoperative acute chest syndrome (ACS), infections, vaso-occlusive pain crises, and 30-day mortality. Children with SCD have […]

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Uncategorized Published - 20 June, 2024    By - Dr Clemens
Pulse Oximetric Pulse Rate: What Are We Measuring?

Authors: Michael Vandenheuvel, MD et al  Anesthesia Patient Safety Foundation June 2024 Volume 39, No. 2 DEAR RAPID RESPONSE: Since the 1970s, the pulse oximeter (PO) has enabled noninvasive continuous assessment of arterial blood oxygenation as well as pulse rate. The pulse estimate is derived from the plethysmographic waveform and serves as a proxy for […]

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Uncategorized Published - 20 June, 2024    By - Dr Clemens
μ-Opioid Receptor Activation at the Dorsal Reticular Nucleus Shifts Diffuse Noxious Inhibitory Controls to Hyperalgesia in Chronic Joint Pain in Male Rats

Authors: Raquel Pereira-Silva, Ph.D. et al  Anesthesiology June 2024, Vol. 140, 1176–1191. Background The dorsal reticular nucleus is a pain facilitatory area involved in diffuse noxious inhibitory control (DNIC) through opioidergic mechanisms that are poorly understood. The hypothesis was that signaling of μ-opioid receptors is altered in this area with prolonged chronic inflammatory pain and that […]

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Uncategorized Published - 19 June, 2024    By - Dr Clemens
What Is the Role of a Periarticular Injection for Knee Arthroplasty Patients Receiving a Multimodal Analgesia Regimen Incorporating Adductor Canal and Infiltration Between the Popliteal Artery and Capsule of the Knee Blocks?

AUTHORS: YaDeau, Jacques T. MD, PhD et al  Anesthesia & Analgesia 138(6):p 1163-1172, June 2024. BACKGROUND: Optimal analgesic protocols for total knee arthroplasty (TKA) patients remain controversial. Multimodal analgesia is advocated, often including peripheral nerve blocks and/or periarticular injections (PAIs). If 2 blocks (adductor canal block [ACB] plus infiltration between the popliteal artery and capsule of […]

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Uncategorized Published - 19 June, 2024    By - Dr Clemens
An Evolving Framework for Using Big Data Tools and Machine Learning to Enhance Perioperative Quality Improvement, Research, and Patient Safety

Authors: Michael R. Mathis, MD et al  Anesthesia Patient Safety Foundation June 2024 Volume 39, No. 2  In an era of near-complete adoption of electronic health records (EHRs) and coalescence of health data across departments and institutions, a growing recognition of practice variation has emerged. Perioperative care is no exception, with recent studies demonstrating wide […]

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