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Authors: Langer, Sarah et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005785 This meta-analysis of randomized controlled trials compared neonatal outcomes following cesarean delivery performed under regional anesthesia (spinal, epidural, or combined spinal-epidural) versus general anesthesia. Although regional techniques are widely preferred for maternal safety and recovery, their comparative effect on neonatal well-being has remained uncertain. […]
Read MoreAuthors: Padilla, Andrew et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005788 This multicenter retrospective cohort study examined anesthetic practices for cesarean hysterectomy in patients with placenta accreta spectrum (PAS) using data from the Multicenter Perioperative Outcomes Group (MPOG) database. Placenta accreta, increta, and percreta represent progressively invasive forms of abnormal placentation associated with massive hemorrhage […]
Read MoreAuthors: Wilson, Jenna et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005649 This prospective randomized controlled trial evaluated whether intraoperative ketamine reduces acute postsurgical pain in women undergoing breast cancer surgery, while also examining whether baseline temporal summation of pain (a measure of central sensitization) influences ketamine’s efficacy. A total of 225 patients were randomized to […]
Read MoreAuthors: Zhu, Youzhuang et al. Anesthesiology October 2025 | DOI: 10.1097/ALN.0000000000005800 This randomized controlled trial evaluated whether S-ketamine can reduce postoperative delirium (POD) in elderly patients undergoing total hip or knee arthroplasty under neuraxial anesthesia. The study enrolled 372 patients between November 2023 and October 2024 at a high-volume arthroplasty center with standardized perioperative care […]
Read MoreAuthors: Shen, Fangming et al. Anesthesiology 2025 Oct 14 | DOI: 10.1097/ALN.0000000000005707 This multicenter randomized clinical trial (the AmPRAEC study) evaluated how different anesthesia-maintenance strategies affect postoperative respiratory adverse events (PRAEs) in children undergoing adenotonsillectomy. The investigators enrolled 760 children aged 0–12 years at 12 hospitals in China and randomly allocated them to one of […]
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