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Anesthesiology Published - 14 January, 2026    By - Dr Clemens
Spectral Differences of Anesthetic Agents: Addressing Fundamental Problems With New Methods

Authors: Dragovic SZ et al. Anesthesia & Analgesia, Volume 142, Issue 2, pages 249–260, February 2026 Summary:This retrospective study examines whether commonly used processed EEG metrics obscure meaningful differences between anesthetic agents, particularly propofol versus volatile fluranes (sevoflurane and desflurane). The authors challenge the “one-size-fits-all” assumption that equivalent processed EEG targets reflect comparable anesthetic brain […]

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Anesthesiology Published - 14 January, 2026    By - Dr Clemens
Efficacy and Safety of Preemptive Magnesium Sulfate Infusion during Pheochromocytoma and Paraganglioma Resection

Authors: Kong H et al. Journal: Anesthesiology, November 25, 2025. DOI: 10.1097/ALN.0000000000005778 SummaryThis randomized, double-blind, placebo-controlled trial evaluated whether preemptive magnesium sulfate infusion improves intraoperative hemodynamic stability during pheochromocytoma and paraganglioma (PPGL) resection—procedures well known for extreme catecholamine-mediated blood pressure and heart rate fluctuations. Ninety-two patients scheduled for PPGL resection were randomized to receive either […]

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Anesthesiology Published - 14 January, 2026    By - Dr Clemens
The anesthesia breakthroughs that defined 2025

Author: Sophie Eydis Becker’s ASC Review Anesthesiology saw a year of significant innovation in 2025 as new technologies, techniques and care models redefined what is possible in the perioperative environment. From AI-driven automation to next-generation pain control, five breakthroughs in particular helped shape the specialty. 1. AI-driven decision support, smart ultrasound and virtual reality-enhanced training […]

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Anesthesiology Published - 13 January, 2026    By - Dr Clemens
Cardiac Biomarkers and Risk Stratification in Liver Transplantation for Acute-on-chronic Liver Failure: Refining Current Risk Models for Improved Prediction of Posttransplant Mortality

Authors: Kwon H-M et al. Journal: Anesthesiology, December 2, 2025. DOI: 10.1097/ALN.0000000000005747 SummaryThis retrospective registry-based study evaluated whether incorporating cardiac biomarkers into existing risk models improves prediction of post–liver transplant mortality in patients with acute-on-chronic liver failure (ACLF). Cardiovascular complications are the leading cause of death after liver transplantation in this population, yet commonly used […]

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Anesthesiology Published - 13 January, 2026    By - Dr Clemens
Liposomal Bupivacaine, Plain Bupivacaine, and Saline for Transversus Abdominis Plane Blocks

Authors: Turan A et al. Journal: Anesthesiology, December 1, 2025. DOI: 10.1097/ALN.0000000000005869 SummaryThis multicenter randomized controlled trial (the CLEVELAND Trial) evaluated whether liposomal bupivacaine provides superior or prolonged analgesia compared with plain bupivacaine or saline when used in single-injection, four-quadrant transversus abdominis plane (TAP) blocks for major abdominal surgery. Given widespread use of liposomal bupivacaine […]

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