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Anesthesiology Published - 30 March, 2026    By - Dr Clemens
Efficacy and Safety of Remimazolam Tosylate versus Propofol for Sedation of Postoperative Mechanically Ventilated Patients in Intensive Care Units

Authors: Guan X et al. Anesthesiology, March 19, 2026, 10.1097/ALN.0000000000006047 Summary This multicenter, randomized, phase 3 non-inferiority trial compared remimazolam tosylate—a short-acting benzodiazepine—to propofol for sedation of postoperative mechanically ventilated ICU patients. The study enrolled 211 patients, almost all postoperative, requiring at least 6 hours of sedation with a target RASS of -2 to +1. […]

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Anesthesiology Published - 30 March, 2026    By - Dr Clemens
Effect of Paroxetine or Escitalopram Co-administered with Oxycodone vs Oxycodone Alone on Ventilation During Hypercapnia

Authors: Florian J et al. Anesthesiology, March 2026, 10.1097/ALN.0000000000006043 Summary This randomized, double-blind, 3-period crossover trial looked at whether chronic SSRI therapy changes ventilatory response to hypercapnia, either by itself or when combined with oxycodone. Healthy volunteers received paroxetine, escitalopram, and placebo in separate treatment periods, with oxycodone 10 mg added on study days 6, […]

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Anesthesiology Published - 30 March, 2026    By - Dr Clemens
3 studies scaring anesthesiologists

Author: Francesca Mathewes Becker’s ASC Review From the persistence of opioid dependency in patients post-procedure to workforce strain and decline, there are a number of trends putting increased pressure on anesthesiologists and their teams. Here are three recent studies scaring anesthesiologists: 1. A growing number of patients undergoing major surgery are receiving medication for opioid use […]

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Anesthesiology Published - 30 March, 2026    By - Dr Clemens
Match Day 2026 Sets Records, but Key Specialties See Fill Rates Drop

Author: Alexis Pellek MedCentral News Congratulations to the class of 2026 – Match Day is here! Soon-to-be medical school graduates around the country simultaneously opened their envelopes today to reveal where they would spend their residency for the next several years. This year broke records as the largest Match Day in history. Match Day is the culmination […]

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Anesthesiology Published - 27 March, 2026    By - Dr Clemens
Preoperative Cannabis Use and Postoperative Delirium in Older Adults Undergoing Major Noncardiac Surgery

Authors: Delaporte A et al. Anesthesiology Open 1(1): e0007, January 2026 SummaryCannabis use is increasing among older adults, particularly in regions where medical or recreational use is legal. Despite this trend, the perioperative implications of cannabis exposure remain poorly understood. Because cannabinoids interact with neural pathways involved in arousal, attention, and memory, investigators have hypothesized […]

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