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Uncategorized Published - 13 January, 2015    By - Dr Clemens
Invasive Treatments for Complex Regional Pain Syndrome in Children and Adolescents: A Scoping Review

Published in Journal of the American Society of Anesthesiologists 12 2014. Authors: Boris Zernikow, M.D., Ph.D et al This review aimed to synthesize the current evidence on the effectiveness of invasive treatments for complex regional pain syndrome in children and adolescents. Studies on children and adolescents with complex regional pain syndrome that evaluated the effects […]

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Uncategorized Published - 13 January, 2015    By - Dr Clemens
Up-regulation of MicroRNA-21 Mediates Isoflurane-induced Protection of Cardiomyocytes

Published in Journal of the American Society of Anesthesiologists in 2/2015. Authors: Jessica M. Olson, M.S. et al Background: Anesthetic cardioprotection reduces myocardial infarct size after ischemia–reperfusion injury. Currently, the role of microRNA in this process remains unknown. MicroRNAs are short, noncoding nucleotide sequences that negatively regulate gene expression through degradation or suppression of messenger […]

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Uncategorized Published - 13 January, 2015    By - Dr Clemens
Feasibility of Closed-loop Titration of Propofol and Remifentanil Guided by the Bispectral Monitor in Pediatric and Adolescent Patients: A Prospective Randomized Study

Published in Journal of the American Society of Anesthesiologists 12 2014 Authors: Gilles A. Orliaguet, M.D., Ph.D. et al Background: This study was designed to assess the feasibility of dual closed-loop titration of propofol and remifentanil guided solely by the Bispectral Index (BIS) monitor in pediatric and adolescent patients during anesthesia. Methods: Children undergoing elective […]

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Uncategorized Published - 12 January, 2015    By - Dr Clemens
Transfusion Thresholds Should Be Conservative for Patients with Septic Shock

Authors: Holst LB et al., N Engl J Med 2014 Oct 9; 371:1381 Transfusion thresholds of 7 g/dL or 9 g/dL yielded similar outcomes. Patients with septic shock are treated with early antibiotics, rapid fluid resuscitation, vasopressor/inotrope support, and blood transfusions. The Surviving Sepsis guidelines’recommendation for a transfusion hemoglobin target of 7 to 9 g/dL […]

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Uncategorized Published - 12 January, 2015    By - Dr Clemens
Persistent paralysis after spinal anesthesia for cesarean delivery

Published in Journal of Clinical Anesthesia (JCA) (Nov 2014) Authors: Zaphiratos V, McKeen D, Macaulay B, George R Anterior spinal artery syndrome has rarely been reported as a cause of permanent neurologic complications after neuraxial anesthesia in obstetric patients. A parturient developed anterior spinal artery syndrome after spinal anesthesia for cesarean delivery. A healthy 32-year-old […]

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