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Uncategorized Published - 19 February, 2015    By - Dr Clemens
Pharmacokinetics of Tranexamic Acid in Neonates, Infants, and Children Undergoing Cardiac Surgery with Cardiopulmonary Bypass

Published in The Journal of the American Society of Anesthesiologists on 1 2015. Authors: Mark C. Wesley, M.D. et al Background: Tranexamic acid (TXA) is one of the most commonly used antifibrinolytic medications in children undergoing repair of congenital heart defects. However, a pharmacokinetics analysis of TXA has never been performed in neonates or young […]

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Uncategorized Published - 18 February, 2015    By - Dr Clemens
Barriers to Referral for Epilepsy Surgery Evaluation

Published in Neurology 2015 Jan 13; 84:159 Authors: Roberts JI et al. A large national survey in Canada reveals insights into neurologist-related barriers to referral for possible surgical treatment of drug-resistant seizure disorders. Marked underuse of resective surgery for drug-resistant focal epilepsy has not changed in recent decades. Although substantial accumulated evidence has demonstrated safety […]

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Uncategorized Published - 18 February, 2015    By - Dr Clemens
Transfuse Plasma, Platelets, and Red Blood Cells in a 1:1:1 Ratio in Trauma Patients

Published in JAMA 2015 Feb 3; 313:471 Authors: Holcomb JB et al. Compared with a 1:1:2 ratio, the 1:1:1 ratio improved hemostasis without causing more adverse effects, although mortality did not differ. In recent years, the dogma regarding large-volume crystalloid resuscitation in trauma patients has changed, with increased emphasis on including plasma and platelets in […]

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Uncategorized Published - 18 February, 2015    By - Dr Clemens
Neuropathic Pain Therapy: Evidence-Based Recommendations

Published in Lancet Neurol 2015 Feb 14:162 Authors: Finnerup NB et al. Results of a meta-analysis and systematic review Neuropathic pain is a serious chronic condition affecting quality of life that can be relieved but not cured. The estimated prevalence is at least 1% to 5% of the general population (Pain Pract 2014; 14:283). Neuropathic […]

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Uncategorized Published - 18 February, 2015    By - Dr Clemens
A Falling Trend in U.S. Coronary Revascularization Procedures

Published in Circulation 2015 Jan 27; 131:362 Authors: Culler SD et al. Published in Circulation 2015 Jan 27; 131:362 Findings from an analysis of two national Medicare databases To determine recent trends in coronary revascularization among Medicare beneficiaries, researchers analyzed two national administrative databases. The data covered inpatient and outpatient percutaneous coronary interventions (PCIs) and […]

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