AUTHORS: Malewicz-Oeck et al Anesthesia & Analgesia March 25, 2025. BACKGROUND: After fracture-related surgery, chronic posttraumatic and/or postsurgical pain (CPSP) has a high incidence rate of up to 43% a year after surgery. Yet the underlying mechanisms are poorly understood. Murine and clinical evidence suggest immunological modulation of postsurgical pain. However, the specific cytokine profiles […]
Read MoreAUTHORS: Caldwell, Matthew D. MD et al Anesthesia & Analgesia March 27, 2025. BACKGROUND: Clinical experience is foundational to graduate medical education but is difficult to quantify. Self-reported case logs and scheduled rotations provide limited detail on residents’ actual experiences. The analysis of electronic health record (EHR) data may provide a more comprehensive view of […]
Read MoreAUTHORS: Sharpe, Emily E. MD et al Anesthesia & Analgesia April 04, 2025. BACKGROUND: Childbirth can have a substantial impact on maternal health-related quality of life. Cesarean delivery is the most performed inpatient operation, yet little is known about normal postpartum recovery profiles. The primary aim of our study was to longitudinally evaluate global health […]
Read MoreAUTHORS: Arina, Pietro et al Anesthesia & Analgesia March 31, 2025. BACKGROUND: This study investigates the role of metabolic flexibility in determining perioperative outcomes. Metabolic flexibility, a key feature of metabolic health, is the ability to efficiently switch between different fuel sources (predominantly carbohydrates and fats) depending on energy demands and availability. Given the rapidly […]
Read MoreAUTHORS: Stewart, Kenneth E. PhD et al Anesthesia & Analgesia April 04, 2025. BACKGROUND: Advances in blood conservation have reduced the need for allogeneic transfusions in total knee and hip arthroplasty (TKA/THA). This study aimed to assess whether perioperative bleeding complications, including hemorrhage/hematoma, allogeneic transfusions, and postoperative anemia, occurred at similar rates between patients with […]
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