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Uncategorized Published - 3 June, 2025    By - Dr Clemens
Effect of Ketamine on the Bispectral Index, Spectral Edge Frequency, and Surgical Pleth Index During Propofol-Remifentanil Anesthesia

AUTHORS: Linassi, Federico MD et al Anesthesia & Analgesia 140(6):p 1276-1285, June 2025. BACKGROUND: Ketamine administration during stable propofol anesthesia is known to be associated with an increase in bispectral index (BIS) but a “deepening” in the level of hypnosis. This study aimed to evaluate the association between the effect-site concentration of ketamine (CeK) and 2 […]

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Uncategorized Published - 3 June, 2025    By - Dr Clemens
Empowering Clinicians: A Comprehensive Guide to Navigating Pain Management for Peripartum Opioid-Use Disorder

Authors: Townsel, Courtney D. MD et al Anesthesia & Analgesia 140(6):p 1314-1317, June 2025. Opioid-use disorder (OUD) in pregnancy increased significantly in the past decade1 and is a leading cause of maternal morbidity and mortality in the United States,2 primarily due to opioid overdose and co-occurring mental health conditions. Notably for readers of Anesthesia & Analgesia, the quality of […]

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Uncategorized Published - 3 June, 2025    By - Dr Clemens
Systemic Inflammatory Response Syndrome Following High-Dose Intravenous Glutathione-Containing Revitalising Solution in a Patient on Tirzepatide

Authors: Sharma D et al Cureus 17(5): e84736. doi:10.7759/cureus.84736 Abstract Intravenous glutathione-based products are increasingly used for cosmetic purposes despite lacking regulatory approval in the United Kingdom and robust safety data. We report a case of systemic inflammatory response syndrome (SIRS) following administration of Glutax 75GX DCRP, a high-dose unregulated glutathione infusion, in a patient […]

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Uncategorized Published - 3 June, 2025    By - Dr Clemens
Intravenous Dabigatran Provides Effective, Reversible Anticoagulation for Cardiopulmonary Bypass in a Sheep Model

Authors: Nadtochiy, Sergiy M PhD et al Anesthesiology ():10.1097/ALN.0000000000005580, May 27, 2025. Background Heparin is the standard anticoagulant used during Cardiopulmonary Bypass (CPB). However, there are problems with heparin, including immunogenicity and variability of effect, that make a search for an alternative desirable. We have reported that dabigatran anticoagulation provides adequate conditions for CPB in a […]

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Uncategorized Published - 3 June, 2025    By - Dr Clemens
Illinois anesthesia time limit bill passes Senate

Author: Claire Wallace Becker’s ASC Review A bill that would ban anesthesia time limits in Illinois has unanimously passed out of the state Senate, according to a May 22 report from WAND. The bill was proposed in January by Republican Illinois state Rep. Bill Hauter, MD, in response to a policy floated by Anthem Blue Cross Blue Shield in […]

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