PUBLISHED: BJOG. 2015 Jan 5. doi: 10.1111/1471-0528.13249 AUTHORS: Fleet J el at OBJECTIVE: To compare the efficacy of fentanyl administered via the subcutaneous (s.c.) or intranasal (i.n.) route with intramuscular (i.m.) pethidine in labouring women requesting analgesia. DESIGN: A randomised controlled trial three-armed, parallel-design. SETTING: A regional hospital and the largest tertiary maternity centre in South […]
Read MorePublished in J Clin Anesth. 2015 May;27(3):226-32 AUTHORS: Delfino AE et al STUDY OBJECTIVE: The study objective was to establish the impact of acute hypertension on morphine’s requirements after laparoscopic cholecystectomy. DESIGN: The design was a randomized, simple blinded study. SETTING: The settings were operating room, postoperative recovery area, and first postoperative day. PATIENTS: There were […]
Read MorePublished in J Clin Anesth. 2015 Mar;27(2):105-10 AUTHORS: Pinar HU et al STUDY OBJECTIVE: To investigate the effect of 6% hydroxyethyl starch (HES) (130/0.4) infusion on ischemia-reperfusion determinants in minor lower extremity operations with tourniquet application. DESIGN: Prospective, randomized, clinical trial. SETTING: University hospital operation room. PATIENTS: American Society of Anesthesiologists I and II 40 patients […]
Read MoreThis is another post for our pain providers to read. The study was published in Drug and Alcohol Dependence. As users of heroin and other opioids get older, their risk for overdose death increases dramatically, a new study of age trends in excess deaths shows. Although male users had almost double the rate of drug-related poisoning in early […]
Read MoreAfter tonsillectomy, ibuprofen in combination with acetaminophen provides safe, effective analgesia for children. In contrast, morphine can cause life-threatening oxygen desaturation in certain children, and therefore its use should be avoided when possible. Lauren E. Kelly, PhD, from Western University, London, Ontario, Canada, and colleagues published the results of their prospective clinical trial in Pediatrics. Their study […]
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