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Uncategorized Published - 28 April, 2015    By - Dr Clemens
Single-dose systemic acetaminophen to prevent postoperative pain: a meta-analysis of randomized controlled trials

Published in Clin J Pain. 2015 Jan;31(1):86-93 Authors: De Oliveira GS Jr et al OBJECTIVES: The effect of a single-dose systemic acetaminophen to treat postoperative pain has been previously quantified, but the effect of systemic acetaminophen to prevent postoperative pain is currently not well defined. The preventive analgesic effect of acetaminophen has yet to be […]

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Uncategorized Published - 28 April, 2015    By - Dr Clemens
Postoperative pain after laparoscopic cholecystectomy is not reduced by intraoperative analgesia guided by analgesia nociception index (ANI®) monitoring: a randomized clinical trial

Published in Br J Anaesth. 2015 Apr;114(4):640-5 Authors: Szental JA et al BACKGROUND: Laparoscopic cholecystectomy frequently results in significant immediate postoperative pain. A new pain monitor, analgesic nociception index (ANI(®)), based on heart rate variability, has recently been approved for intraoperative nociception monitoring. We designed a single-blind, parallel-group, randomized control trial to test the hypothesis […]

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Uncategorized Published - 28 April, 2015    By - Dr Clemens
Effects of different remifentanil target concentrations on MAC BAR of sevoflurane in gynaecological patients with CO2 pneumoperitoneum stimulus

Published in Br J Anaesth. 2015 Apr;114(4):634-9 Authors: Zou ZY et al BACKGROUND: To investigate the effects of different target plasma remifentanil concentrations on the minimum alveolar concentration of sevoflurane (MAC) for blocking adrenergic response (BAR) during laparoscopic gynaecological surgery with carbon dioxide insufflation. METHODS: Seventy-five gynaecological patients with ASA I-II undergoing laparoscopic surgery were […]

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Uncategorized Published - 28 April, 2015    By - Dr Clemens
Does bupivacaine and fentanyl combination for epidural analgesia shorten the duration of labour?

Published in J Obstet Gynaecol. 2014 Dec 29:1-4 Authors: Genc M et al In this study we aimed to explore the effects of epidural analgesia achieved by a combination of low-dose bupivacaine and fentanyl infused through an epidural catheter on mother, foetus and labour process in nulliparous at-term pregnant women during vaginal delivery. This study […]

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Uncategorized Published - 28 April, 2015    By - Dr Clemens
Pain and Depression Treatment Possible in Fibromyalgia

Patients with fibromyalgia can safely be treated with the anticonvulsant drug pregabalin (Lyrica, Pfizer Inc) for their pain while at the same time being treated for depression, a new study shows. Results of a double-blind study showed that pregabalin significantly improved mean pain scores compared with placebo in patients with fibromyalgia taking a selective serotonin […]

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