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Uncategorized Published - 18 March, 2015    By - Dr Clemens
Postoperative Mortality Among HIV-Infected Patients

Authors: King JT Jr et al., JAMA Surg 2015 Feb 25; Thirty-day mortality, although relatively low, was still higher than for HIV-uninfected patients. Now that HIV-infected individuals have a near-normal life expectancy, they are increasingly likely to undergo surgical procedures. How do their short-term surgical outcomes compare with those of HIV-uninfected patients? To answer this question, investigators studied […]

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Uncategorized Published - 18 March, 2015    By - Dr Clemens
Zoster Vaccine Efficacy: How Long?

Authors: Whitley RJ., Clin Infect Dis 2015 Mar 15; 60:910 This is for our providers that take care of chronic pain patients. After 10 years, vaccination lost most of its power. Short-term follow-up of participants in placebo-controlled studies of the herpes zoster (HZ) vaccine confirmed that the vaccine was efficacious for at least 5 years (NEJM JW […]

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Uncategorized Published - 17 March, 2015    By - Dr Clemens
FDA Clears Hydrocodone With Abuse-Deterrent Properties

The US Food and Drug Administration (FDA) has approved the extended-release (ER) single-entity opioid analgesic hydrocodone bitartrate (Hysingla ER, Purdue Pharma) with abuse-deterrent properties in line with the FDA’s 2013 draft guidance to industry, the agency announced. “Hysingla ER has properties that are expected to reduce, but not totally prevent, abuse of the drug when […]

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Uncategorized Published - 17 March, 2015    By - Dr Clemens
Rocuronium Blockade Reversal With Sugammadex vs. Neostigmine

Randomized Study in Chinese and Caucasian Subjects Authors: Xinmin Wu et al Published in BMC Anesthesiol. 2014;14(53) Background This study compared efficacy and safety of the selective relaxant binding agent sugammadex (2 mg/kg) with neostigmine (50 μg/kg) for neuromuscular blockade (NMB) reversal in Chinese and Caucasian subjects. Methods This was a randomized, active-controlled, multicenter, safety-assessor-blinded study (NCT00825812) in […]

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Uncategorized Published - 17 March, 2015    By - Dr Clemens
Comparison of pain outcomes between two anti-GD2 antibodies in patients with neuroblastoma

Article of our pain providers. Published in Pediatr Blood Cancer © 2014 Wiley Periodicals, Inc. Author(s): Anghelescu D, Goldberg J, Faughnan L, Wu J, Mao S, Furman W, Santana V, Navid F Treatments discussed: ch14.18, morphine BACKGROUND Addition of anti-GD2 antibody ch14.18 to the treatment of neuroblastoma has improved outcomes. The most common side effect of ch14.18 […]

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