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Uncategorized Published - 5 May, 2015    By - Dr Clemens
Volume guarantee ventilation during surgical closure of patent ductus arteriosus

Published in Am J Perinatol. 2015 Jan;32(1):23-6. Authors: Keszler M et al BACKGROUND: Surgical closure of patent ductus arteriosus (PDA) is associated with adverse outcomes. Surgical exposure requires retraction of the lung, resulting in decreased aeration and compliance. Optimal respiratory support for PDA surgery is unknown. Experience with volume guarantee (VG) ventilation at our institution led […]

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Uncategorized Published - 5 May, 2015    By - Dr Clemens
Is the serum level of reactive oxygen metabolites appropriate for evaluating short-term surgical stress of patients undergoing colectomy?

Publsihed in Int Surg. 2015 Apr;100(4):770-2. Authors: Fujita F et al To demonstrate whether reactive oxygen and free radical measuring are appropriate to evaluate short-term surgical stress after laparoscopic colectomy. The subjects consisted of 22 cases (laparoscopic surgery, 16; and laparotomy, 6) that underwent surgery for colon cancer. The reactive oxygen metabolites (ROM) value in the […]

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Uncategorized Published - 5 May, 2015    By - Dr Clemens
Transfusion Threshold for Abdominal Cancer Surgery Patients

Authors: Pinheiro de Almeida J et al., Anesthesiology 2015 Jan 122:29 A hemoglobin level of 9 g/dL was superior to 7 g/dL as a trigger for transfusion. Randomized trials have shown favorable outcomes with a restrictive red-cell transfusion strategy — that is, not transfusing until hemoglobin levels are <7 g/dL in general critical-care patients (NEJM JW Gen […]

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Uncategorized Published - 5 May, 2015    By - Dr Clemens
Population pharmacokinetic model of free and total ropivacaine after TAP nerve block in patients undergoing liver resection.

Published in Br J Clin Pharmacol. 2014 Dec 31 Authors: Ollier E et al AIM: The aim of this study was to develop a pharmacokinetic model in order to characterise the free and total ropivacaine concentrations after TAP block in a population of patients undergoing liver resection surgery. In particular, we evaluated the impact of the […]

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Uncategorized Published - 5 May, 2015    By - Dr Clemens
Methadone dose in heroin-dependent patients: role of clinical factors, comedications, genetic polymorphisms and enzyme activity.

Published in Br J Clin Pharmacol. 2014 Dec 30. Authors: Mouly S et AIMS: Methadone is characterized by wide intersubject variability regarding the dose needed to obtain full therapeutic response. We assessed the influence of sociodemographic, ethnic, clinical, metabolic & genotype variables on methadone maintenance dose requirement in opioid-dependent responder patients. METHODS: Eighty-one stable patients (60 […]

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