Authors: Holcomb JB et al. JAMA 2015 Feb 3. Compared with a 1:1:2 ratio, the 1:1:1 ratio improved hemostasis without causing more adverse effects, although mortality did not differ. In recent years, the dogma regarding large-volume crystalloid resuscitation in trauma patients has changed, with increased emphasis on including plasma and platelets in addition to red blood cells […]
Read MoreDespite effective new treatments for their disease, children with pulmonary hypertension (PHT) are still a high-risk group for serious complications and death related to anaesthesia and surgery, according to a study published in the February issue of the journal Anesthesia & Analgesia. “The risk for adverse events during anaesthesia in patients with PHT remains high, […]
Read MoreTreating post-operative pain with morphine can cause life-threatening respiratory problems in some children who have had their tonsils and/or adenoids removed, according to a study published in the January 26, 2015, online edition of the journal Pediatrics. The study has identified a significant risk for potentially-fatal breathing disruption when morphine is administered at home after […]
Read MoreIt is disturbingly common, dangerously lethal and difficult to diagnose, yet propofol-related infusion syndrome (PRIS) may be detected before it happens, given proper vigilance by anesthesiologists. Indeed, research has found a positive correlation between the duration of propofol infusion and increasing triglyceride (TG) levels, which may indicate onset of the deadly complication. “Obviously, propofol has […]
Read MorePublished in Clinical Interventions in Aging 10 1-11 (2015) Authors: Guerriero F et al PURPOSE Chronic pain is highly prevalent in older adults. Increasing evidence indicates strong opioids as a valid option for chronic pain management in geriatrics. The aim of this study was to evaluate efficacy and safety of low-dose oral prolonged-release oxycodone-naloxone (OXN-PR) in […]
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