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Uncategorized Published - 5 March, 2015    By - Dr Clemens
Predictors of Clinically Significant Postoperative Events after Open Craniosynostosis Surgery

Authors: Susan M. Goobie, M.D., F.R.C.P.C. et al Published in Anesthesiology 2 2015. Background: Craniosynostosis surgery is associated with clinically significant postoperative events requiring intensive care unit (ICU) admission. The authors investigate specific variables, which might influence the risk for these events, and thereby make recommendations regarding the need for postoperative ICU admission. Methods: A retrospective review of […]

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Uncategorized Published - 5 March, 2015    By - Dr Clemens
Genetic and Clinical Factors Associated with Chronic Postsurgical Pain after Hernia Repair, Hysterectomy, and Thoracotomy: A Two-year Multicenter Cohort Study

Published in Anesthesiology 2 2015. Authors: Antonio Montes, M.D., Ph.D. et al Background: Chronic postsurgical pain (CPSP) has been linked to many surgical settings. The authors aimed to analyze functional genetic polymorphisms and clinical factors that might identify CPSP risk after inguinal hernia repair, hysterectomy, and thoracotomy. Methods: This prospective multicenter cohort study enrolled 2,929 patients scheduled for […]

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Uncategorized Published - 5 March, 2015    By - Dr Clemens
Adenosine Monophosphate–activated Protein Kinase Regulates Interleukin-1β Expression and Glial Glutamate Transporter Function in Rodents with Neuropathic Pain

Authors: Dylan W. Maixner, B.S. et al Anesthesiology Published on 2 2015 Background: Neuroinflammation and dysfunctional glial glutamate transporters (GTs) in the spinal dorsal horn are implicated in the genesis of neuropathic pain. The authors determined whether adenosine monophosphate–activated protein kinase (AMPK) in the spinal dorsal horn regulates these processes in rodents with neuropathic pain. Methods: Hind paw […]

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Uncategorized Published - 5 March, 2015    By - Dr Clemens
How to Differentiate Traumatic Lumbar Punctures from Aneurysmal Subarachnoid Hemorrhage

Authors: Perry JJ et al., BMJ 2015 Feb 18; 350:h568 The combination of a red blood cell count less than 2000 × 10^6/L and no xanthochromia is sufficient to rule out aneurysmal SAH in patients with traumatic lumbar punctures. The diagnosis of subarachnoid hemorrhage (SAH) often requires lumbar puncture (NEJM JW Emerg Med Mar 2013 and Ann Emerg Med 2013; […]

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Uncategorized Published - 4 March, 2015    By - Dr Clemens
NSAIDs Are a Major Cause of Anaphylaxis-Related Emergency Department Visits

This is for our provider that treat chronic pain patients. Published in J Allergy Clin Immunol Pract 2014 Jul/Aug 2:414 Authors: Aun MV et al. Epinephrine is first-line treatment for drug-induced anaphylaxis, but it is underutilized. Anaphylaxis is a life-threatening hypersensitivity reaction that can be allergic or nonallergic. Allergic causes of drug-induced anaphylaxis generally are IgE mediated […]

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