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Published in Acta Anaesthesiol Scand. 2015 Mar;59(3):406-7 Authors: D’souza S et al Abstract A descriptive case report of a 22-year-old woman, scheduled for elective laparotomy who had a respiratory arrest after premedication with inj glycopyrrolate and ondansetron. Respiratory arrest is an uncommon side effect of glycopyrrolate with very few published reports. Ondansteron can also cause […]
Read MorePublished in Anaesth Crit Care and Pain. 2014;14(5):224-229 Authors: Susan M Nimmo MB ChB FRCA FFPMRCA FRCPEdin MSc Pain Medicine et al Many of the benefits of effective epidural analgesia for open abdominal surgery are soundly established. A well-managed epidural can provide excellent analgesia in the postoperative period allowing the patient to be pain free […]
Read MoreIn a drug safety communication issued today, the US Food and Drug Administration (FDA) says it is aware of recent reports “questioning” the safety of prescription and over-the-counter (OTC) pain medicines when used during pregnancy, but that it lacks adequate studies to change current recommendations. The benefits and risks of using prescription and OTC pain […]
Read MorePublished in Br J Anaesth. 2015 Feb;114(2):281-9 Authors: Rehberg B et BACKGROUND: The safety of patient-controlled i.v. analgesia (PCA) with remifentanil for obstetrical analgesia remains a matter of concern. The efficacy of remifentanil bolus application, that is, the coincidence between pain and remifentanil effect-site concentration, may be improved by forecasting contractions, but it is not […]
Read MorePublished in Br J Anaesth. 2015 Apr;114(4):605-14 Authors: Liu N et al BACKGROUND: We used an automated bispectral index (BIS)-guided dual-loop controller to determine propofol and remifentanil requirements during general anaesthesia in obese and lean surgical patients. METHODS: Obese patients, BMI>35 kg m(-2), and lean patients (<25 kg m(-2)) having laparoscopic procedures were prospectively evaluated […]
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