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Although 15 years have passed since the last airway injury analysis of the American Society for Anesthesiologists (ASA) Closed Claims Project, new research reveals that pharyngeal and esophageal perforations continue to be a significant source of patient morbidity and mortality—as well as liability for anesthesiologists. The investigators noted, however, that practitioner diligence is key to […]
Read MorePublished in Acta Anaestesiol Scand 2015 Apr;59(4):414-26 Authors: Heesen M et al BACKGROUND: Intravenous ketamine has been used during general and regional anaesthesia for caesarean section. No systematic review and meta-analysis on the desired effects and adverse effects of ketamine administration during caesarean section have yet been performed. METHODS: After a systematic literature search a meta-analysis was […]
Read MorePublished in Acta Anaesthesiol Scand. 2015 Apr;59(4):496-504 Authors: Telnes A et al BACKGROUND: Multiple studies suggest that transversus abdominis plane (TAP) block (without intrathecal morphine) after Caesarean section (CS) reduces post-operative morphine consumption. In our study, we wanted to compare the analgesic effect of TAP block with infiltration of the wound after CS. METHODS: We included […]
Read MoreAuthors: Mouncey PR et al., N Engl J Med 2015 Apr 2; 372:1301 A third trial shows no benefit for early goal-directed therapy for septic shock. In 2001, a single-center randomized trial demonstrated a significant mortality benefit for early goal-directed therapy (EGDT) in patients with septic shock (NEJM JW Gen Med Dec 15 2001 and N Engl J Med 2001; […]
Read MoreOpioid-induced hyperalgesia is among the most pressing concerns in the national discussion of opioid addiction, underscored by the US Food and Drug Administration’s (FDA) call for clinical trials to better understand the risks, but the issue is mired in more complexities and confusion than many may even realize, an expert says. Norman Harden, MD, from […]
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