Acta Anaesthesiol Scand. 2015 May 5. doi: 10.1111/aas.12521. Authors: Kurita GP et al BACKGROUND: Renal impairment and the risk of toxicity caused by accumulation of opioids and/or active metabolites is an under-investigated issue. This study aimed at analysing if symptoms/adverse effects in opioid-treated patients with cancer were associated with renal function. METHODS: Cross-sectional multicentre study (European Pharmacogenetic […]
Read MoreActa Anaesthesiol Scand. 2015 April;59(7):921-7 Authors: Marashi SM et al BACKGROUND: In this study, the effect of naloxone on duration of supraclavicular brachial plexus block was evaluated. It was hypothesized that naloxone can increase the duration of neural blockade. METHODS: Sixty-eight patients scheduled for surgery under supraclavicular brachial plexus block were randomly assigned to receive 30 ml bupivacaine […]
Read MoreAnesthesia & Analgesia: June 2015 Vol 120 Issue 6 p 1405-1412 Authors: Hausman, Mark S. Jr. MD et BACKGROUND: Surgical patients with chronic obstructive pulmonary disease (COPD) are at increased risk of perioperative complications. In this study, we sought to quantify the benefit of avoiding general anesthesia in this patient population. METHODS: Data from the […]
Read MoreAnesthesia & Analgesia: June 2015 Vol 120 Issue 6 p 1369-1374 Authors: Radvansky, Brian M. BA et al BACKGROUND: Expert witnesses serve a crucial role in the medicolegal system, interpreting evidence so that it can be understood by jurors. Guidelines have been established by both the legal community and professional medical societies detailing the expectations […]
Read MoreAnesthesia & Analgesia: June 2015 Vol 120 Issue 6 p1352-1360 Authors: Malcharek, Michael J. MD et al BACKGROUND: Methods for detecting intraoperative cerebral ischemia arising from internal carotid artery (ICA) cross-clamping during carotid endarterectomy (CEA) should be sensitive, specific, and rapid to prevent intraoperative stroke. We had 3 objectives pertaining to this: (1) investigation of […]
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