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Anesthesia & Analgesia: August 2015 AUTHORS: Li, Yuwen PhD et al BACKGROUND: The anesthetic propofol is thought to induce rapid hypnotic sedation by potentiating [gamma]-aminobutyric acid receptor (GABAAR) activity. Little is known about the molecular mechanisms of propofol in modulating inhibitory synaptic transmission. We aimed to investigate the role of propofol in modulating surface expression […]
Read MoreA new study suggests that a routine hospital stay can disturb the balance of the microbiome so much that it sets up some older individuals for life-threatening sepsis. Researchers found that older adults are three times more likely to develop sepsis, a systemic catastrophic response to infection, in the first three months after leaving a […]
Read MorePaediatr Anaesth 2015 Oct;25(10):1020-5 AUTHORS: Rosandwr S et al BACKGROUND: Children with attention-deficit hyperactivity disorder (ADHD) may experience pain differently compared to other children, yet the evidence is equivocal regarding whether pain is heightened or dampened. This prospective observational study, therefore, was designed to compare the postoperative pain experiences in children with and without ADHD. METHODS: Children […]
Read MoreAnesthesia & Analgesia: October 2015 – Volume 121 – Issue 4 – p 1001–1010 AUTHORS: Bailey, Kristen M. MSc et al BACKGROUND: The purpose of this study is to compare the effectiveness of a brief preparation intervention for parental presence during induction of anesthesia (PPIA preparation) with a PPIA with standard preparation (PPIA standard). METHODS: […]
Read MoreAnesthesia & Analgesia: October 2015 – Volume 121 – Issue 4 – p 861–867 AUTHORS: Klinger, Rebecca Y. MD, MS et al BACKGROUND: Hypomagnesemia has been associated with an increased risk of postoperative atrial fibrillation (POAF). Although previous studies have suggested a beneficial effect of magnesium (Mg) therapy, almost all of these are limited by […]
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