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Uncategorized Published - 16 July, 2015    By - Dr Clemens
A new treatment paradigm for trigeminal neuralgia using Botulinum toxin type A.

Laryngoscope. 2014 Feb;124(2):413-7 Authors: Guardiani E et al OBJECTIVES: To review the current data for the use of Botulinum toxin type A (BoNT-A) in trigeminal neuralgia (TN) and to describe the preferred injection technique of BoNT-A in TN. To propose a new treatment paradigm for TN incorporating the use BoNT-A. DATA SOURCES: MEDLINE and Google Scholar databases. […]

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Uncategorized Published - 16 July, 2015    By - Dr Clemens
Combined saphenous and sciatic catheters for analgesia after major ankle surgery: a double-blinded randomized controlled trial

Can J Anaesth. 2015 Aug;62(8):875-882 Authors: Fisker AK et al PURPOSE: Continuous sciatic nerve block is used for pain management following major ankle surgery. Pain from the saphenous nerve territory often persists. We conducted a double-blinded randomized placebo-controlled trial to evaluate the effect of a supplementary saphenous catheter in the proximal thigh combined with a popliteal sciatic […]

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Uncategorized Published - 16 July, 2015    By - Dr Clemens
A naloxone admixture to prevent opioid-induced pruritus in children: a randomized controlled trial

Can J Anaesth 2015 Aug;62(8):891-900 Authors: West N et al PURPOSE: Morphine administered by continuous opioid infusion (COI) or by patient-controlled analgesia (PCA) is associated with opioid-induced pruritus (OIP). Intravenous naloxone administered separately to the morphine infusion at a dose of 0.25-1.65 μg·kg-1·hr-1 can provide effective prevention from OIP. Nevertheless, this strategy requires a dedicated intravenous line and […]

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Uncategorized Published - 16 July, 2015    By - Dr Clemens
Efficacy of dexmedetomidine on postoperative shivering: a meta-analysis of clinical trials.

Can J Anaesth. 2015 Jul;62(7):816-829 Authors: Liu ZX et al PURPOSE: Shivering is a frequent complication in the postoperative period. The aim of the current meta-analysis was to assess the efficacy of dexmedetomidine on postoperative shivering. METHODS: Two researchers independently searched PubMed, EMBASE™ and the Cochrane Central Register of Controlled Trials for controlled clinical trials. The meta-analysis […]

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Uncategorized Published - 15 July, 2015    By - Dr Clemens
Rates of opioid dispensing and overdose after introduction of abuse-deterrent extended-release oxycodone and withdrawal of propoxyphene.

JAMA Intern Med. 2015 Jun;175(6):978-87 Authors: Larochelle MR et al IMPORTANCE: In the second half of 2010, abuse-deterrent extended-release oxycodone hydrochloride (OxyContin; Purdue Pharma) was introduced and propoxyphene was withdrawn from the US market. The effect of these pharmaceutical market changes on opioid dispensing and overdose rates is unknown. OBJECTIVE: To evaluate the association between 2 temporally […]

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