Authors: G. Landoni, et al Published in Br J Anaesth. 2013;111(6):886-896. Background. Many studies have compared desflurane, isoflurane, sevoflurane, total i.v. anaesthesia (TIVA), or all in cardiac surgery to assess their effects on patient survival. Methods. We performed standard pairwise and Bayesian network meta-analyses; the latter allows indirect assessments if any of the anaesthetic agents were not compared […]
Read MorePublished in Br J Anaesth. 2014;112(3):427-439. Authors: S. Choi, et al Background. Brachial plexus nerve blocks (BPBs) have analgesic and opioid sparing benefits for upper extremity surgery. Single-injection techniques are limited by the pharmacological duration and therapeutic index of local anaesthetics (LAs). Continuous catheter techniques, while effective can present management challenges. Off-label use of perineural dexamethasone as […]
Read MoreMultimodal perioperative analgesia with paravertebral nerve block (PVB) and gabapentin decreases the length of hospitalisation and narcotic usage in patients undergoing mastectomy compared to conventional postoperative management with on-demand postoperative medications (CPM), according to a study presented here at the 37th Annual San Antonio Breast Cancer Symposium (SABCS). The researchers say that the multimodality approach […]
Read MorePublished in J Clin Anesth. 2015 Mar;27(2):159-63 Authors: Kaur Makkar J et al STUDY OBJECTIVE: To evaluate the efficacy and safety profile of paracetamol in comparison with tramadol for pain relief during active labor. DESIGN: Prospective, randomized, double-blind study. SETTING: Maternity Wing of the Postgraduate Institute of Medical Education and Research, Chandigarh. PATIENT: Sixty laboring, […]
Read MorePublished in CMAJ. 2014 Dec 9;186(18):1358-63 Authors: Poonai N et al BACKGROUND: Recent warnings from Health Canada regarding codeine for children have led to increased use of nonsteroidal anti-inflammatory drugs and morphine for common injuries such as fractures. Our objective was to determine whether morphine administered orally has superior efficacy to ibuprofen in fracture-related pain. […]
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