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Uncategorized Published - 18 November, 2015    By - Dr Clemens
Minor Postoperative Increases of Creatinine Are Associated with Higher Mortality and Longer Hospital Length of Stay in Surgical Patients

Authors: Felix Kork, MD et al Anesthesiology 12 2015, Vol.123, 1301-1311 Background: Surgical patients frequently experience postoperative increases in creatinine levels. The authors hypothesized that even small increases in postoperative creatinine levels are associated with adverse outcomes. Methods: The authors examined the association of postoperative changes from preoperative baseline creatinine with all-cause in-hospital mortality and hospital length of […]

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Uncategorized Published - 18 November, 2015    By - Dr Clemens
Oral Midodrine Hydrochloride for Prevention of Orthostatic Hypotension during Early Mobilization after Hip Arthroplasty: A Randomized, Double-blind, Placebo-controlled Trial

Authors: Oivind Jans, MD. PhD et al Anesthesiology 12 2015, Vol.123, 1292-1300 Background: Early postoperative mobilization is essential for rapid recovery but may be impaired by orthostatic intolerance (OI) and orthostatic hypotension (OH), which are highly prevalent after major surgery. Pathogenic mechanisms include an insufficient postoperative vasopressor response. The oral α-1 agonist midodrine hydrochloride increases vascular resistance, […]

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Uncategorized Published - 18 November, 2015    By - Dr Clemens
Perioperative Mortality, 2010 to 2014: A Retrospective Cohort Study Using the National Anesthesia Clinical Outcomes Registry

Authors: Elizabeth L. Whitlock, MD et al Anesthesiology 12 2015, Vol.123, 1312-1321. Background: The National Anesthesia Clinical Outcomes Registry collects demographic and outcome data from anesthesia cases, with the goal of improving safety and quality across the specialty. The authors present a preliminary analysis of the National Anesthesia Clinical Outcomes Registry database focusing on the rates of […]

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Uncategorized Published - 18 November, 2015    By - Dr Clemens
Repeated Time-to-event Analysis of Consecutive Analgesic Events in Postoperative Pain

Authors: Rasmus Vestergaard Juul, M.SC et al Anesthesiology 12 2015, Vol.123, 1411-1419 Background: Reduction in consumption of opioid rescue medication is often used as an endpoint when investigating analgesic efficacy of drugs by adjunct treatment, but appropriate methods are needed to analyze analgesic consumption in time. Repeated time-to-event (RTTE) modeling is proposed as a way to describe analgesic […]

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Uncategorized Published - 18 November, 2015    By - Dr Clemens
AHA CPR and Emergency Cardiac Care Guidelines: Updates for 2015

Authors: Neumar RW et al., Circulation 2015 Nov 3; 132:S315 Push hard and fast — but not too hard or too fast! Sponsoring Organization: American Heart Association (AHA) Target Population: Lay public, healthcare providers Background and Objective The AHA has released an evidence-based update to its 2010 guidelines for cardiopulmonary resuscitation (CPR) and emergency cardiovascular care. Key Points Adult […]

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