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Uncategorized Published - 27 November, 2015    By - Dr Clemens
Cerebrospinal Fluid Biomarker for Alzheimer Disease Predicts Postoperative Cognitive Dysfunction

Authors: Lisbeth Evered, B.Sc, M.Biostat, PhD et al Anesthesiology published on 11 2015. Background: Postoperative cognitive dysfunction (POCD) affects 16 to 21% of the elderly 3 months after anesthesia and surgery and is associated with adverse outcomes. The exact cause of POCD remains unknown. The authors hypothesized that elderly individuals with Alzheimer disease (AD) neuropathology, identified by cerebrospinal […]

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Uncategorized Published - 27 November, 2015    By - Dr Clemens
Psychiatric Disorders and Psychopharmacologic Treatment as Risk Factors in Elective Fast-track Total Hip and Knee Arthroplasty

Authors: Christoffer C. Jorgensen MD, et al Anesthesiology 12 2015, Vol.123, 1281-1291. doi:10.1097/ALN.0000000000000632 Background: Psychiatric disorder (PsD) is rarely considered when evaluating perioperative risk factors. Studies on PsD are often limited by use of administrative coding, incomplete follow-up, and lack of preoperative data on psychopharmacological treatment. Methods: A multicenter study with prospective registration on preoperative comorbidity, complete 90-day follow-up, […]

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Uncategorized Published - 27 November, 2015    By - Dr Clemens
Patient-specific Immune States before Surgery Are Strong Correlates of Surgical Recovery

Authors: Gabriela K. Fragiadakis B.A. et al Anesthesiology 12 2015, Vol.123, 1241-1255. doi:10.1097/ALN.0000000000000887 Background: Recovery after surgery is highly variable. Risk-stratifying patients based on their predicted recovery profile will afford individualized perioperative management strategies. Recently, application of mass cytometry in patients undergoing hip arthroplasty revealed strong immune correlates of surgical recovery in blood samples collected shortly after surgery. However, the […]

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Uncategorized Published - 27 November, 2015    By - Dr Clemens
The Future of Cognitive Aids Implemented During Critical Events

Author: Larry M. Silver MD ASA Monitor 11 2015, Vol.79, 40-42. Larry M. Silver, M.D. is Private Practice Anesthesiologist, Coastal Anesthesia Medical Associates; Medical Product Developer for Tahoe Institute of Rural Health Research, San Luis Obispo, California. Acute care cognitive aids (ACCAs) are tools used by clinicians to deliver emergent treatment to patients with acute medical […]

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Uncategorized Published - 27 November, 2015    By - Dr Clemens
Dexmedetomidine versusPropofol Sedation Reduces Delirium after Cardiac Surgery: A Randomized Controlled Trial

Authors: George Diaiani, MD, FRCA, FRCPC, et al Anesthesiology published on 11 2015. Background: Postoperative delirium (POD) is a serious complication after cardiac surgery. Use of dexmedetomidine to prevent delirium is controversial. The authors hypothesized that dexmedetomidine sedation after cardiac surgery would reduce the incidence of POD. Methods: After institutional ethics review board approval, and informed consent, a single-blinded, […]

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