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Delirium may be a troubling consequence of high-risk cardiac surgery in elderly patients, but that can be avoided with the administration of intraoperative dexmedetomidine, according to a team of Toronto researchers. This benefit, they added, does not come with the burden of negative hemodynamic changes. “Delirium affects as many as one in five elderly patients […]
Read MoreStaff breaks are associated with improved surgical outcomes, a study has concluded. However, the study failed to find an association between handoffs and outcomes. Elucidating the relationship between transitions of care and outcomes is critical for determining best practices for safe patient care. “We read with great interest the Cleveland Clinic study, which demonstrated that […]
Read MoreChest. 2015 Oct 22. doi: 10.1378/chest.15-1389 AUTHORS: Klompas M et al BACKGROUND: Current sedation guidelines recommend avoiding benzodiazepines but express no preference for propofol versus dexmedetomidine. In addition, there are limited data on how well randomized controlled trials on sedatives generalize to routine practice where conditions tend to be more varied and complex. METHODS: We gathered […]
Read MoreSurg Endosc. 2015 Oct 20 AUTHORS: Pourladian I et al BACKGROUND: Carbonic acid accumulation, which results from CO2 insufflation, can produce visceral and referred pain in the postoperative setting. Acetazolamide inhibits carbonic anhydrase, an enzyme that accelerates carbonic acid formation. We hypothesized that preoperative administration of acetazolamide would decrease postoperative pain in patients undergoing laparoscopic inguinal herniorrhaphy. […]
Read MoreAmong nearly 1 million active physicians in the U.S., about 6% were involved in at least one paid malpractice claim during a 10-year period ending in 2014, with a total payout of $13.6 billion, researchers said. The vast majority of claims were for death or major or significant physical injury, according to David M. Studdert, LLB, […]
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