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Published in BMJ, 2015 May 14;350:h2102. Authors: Desai RJ et al OBJECTIVE: To provide absolute and relative risk estimates of neonatal abstinence syndrome (NAS) based on duration and timing of prescription opioid use during pregnancy in the presence or absence of additional NAS risk factors of history of opioid misuse or dependence, misuse of other substances, non-opioid […]
Read MoreThe walls have ears, as the saying goes, but so do sedated patients whose smartphones have been set to “record.” In a recently concluded malpractice trial, that fact not only cost a Maryland doctor some money but subsequently her job, as a June 23 story in the Washington Post reports. The case involved a Vienna, Virginia, man […]
Read MorePublished in J Clin Anesth. 2015 May 30. pii: S0952-8180(15)00148-8 Authors: Linganna RE et al STUDY OBJECTIVE AND DESIGN: The mechanism of action of commonly used general anesthetics is largely unknown. One hypothesized mechanism is through modulation of microtubule stability. Taxanes, a subset of chemotherapeutic drugs known to alter microtubule stability and commonly used to treat breast […]
Read MorePublished in Drugs Aging. 2015 Jun;32(6):419-26. Authors: Veal FC et al Abstract Persistent pain affects the elderly disproportionally, occurring in 50 % of elderly community-dwelling patients and 80 % of aged care residents. The management of pain in the elderly and frail patient is complicated because of the risks posed by changes in pharmacokinetics and pharmacodynamics, polypharmacy, and drug-disease […]
Read MoreLiposomal-encased bupivacaine (LEB) is a good, cost-effective medical choice for pain control after breast surgery. Valerie Lemaine, MD, MPH, an assistant professor of plastic surgery and the vice chair for research at Mayo Clinic College of Medicine, Rochester, Minn., reviewed her experience at the 32nd Annual Miami Breast Cancer Conference. She noted that the drug […]
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