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Anesthesia & Analgesia: August 2015 – Volume 121 – Issue 2 – p 383–391 Authors: Thonnerieux, Magalie MD et al BACKGROUND: Alveolar recruitment maneuvers (ARMs) are known to improve perioperative morbidity but can transiently impact cardiac output (CO). This reproducible hemodynamic perturbation creates a clinical opportunity to test multiple devices during acute changes in CO. […]
Read MoreAnesthesia & Analgesia: August 2015 – Volume 121 – Issue 2 – p 366–372 Authors: Fortier, Louis-Philippe MSc, MD, FRCPC et al BACKGROUND: Postoperative residual neuromuscular blockade (NMB), defined as a train-of-four (TOF) ratio of <0.9, is an established risk factor for critical postoperative respiratory events and increased morbidity. At present, little is known about […]
Read MoreAnesthesia & Analgesia: August 2015 – Volume 121 – Issue 2 – p 357–365 Authors: Short, Timothy G. MBChB, MD, FANZCA et al BACKGROUND: An association between relatively deep anesthesia, as guided by the bispectral index (BIS), and increased postoperative mortality has been demonstrated in 6 of 8 published observational studies, but association does not […]
Read MoreAnesthesia & Analgesia: August 2015 – Volume 121 – Issue 2 – p 373–380 Authors: Tassonyi, Edömér MD, PhD, DSc et al BACKGROUND: Pipecuronium is a steroidal neuromuscular blocking agent. Sugammadex, a relaxant binding γ-cyclodextrin derivative, reverses the effect of rocuronium, vecuronium, and pancuronium. We investigated whether sugammadex reverses moderate pipecuronium-induced neuromuscular blockade (NMB) and […]
Read MoreAnesthesia & Analgesia: August 2015-Volume 121-Issue 2-page 302-318 Authors: Lohser, Jens MD et al Lung injury is the leading cause of death after thoracic surgery. Initially recognized after pneumonectomy, it has since been described after any period of 1-lung ventilation (OLV), even in the absence of lung resection. Overhydration and high tidal volumes were thought […]
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