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Uncategorized Published - 19 April, 2016    By - Dr Clemens
Tranexamic Acid Compared with Placebo for Reducing Total Blood Loss in Hip Replacement Surgery: A Randomized Clinical Trial

Anesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 986–995 AUTHORS: Barrachina, Borja MD et al BACKGROUND: Tranexamic acid (TXA) reduces bleeding in patients undergoing hip replacement surgery, but optimal doses and timing have yet to be established. Our primary objective in this study was to assess total blood loss 48 […]

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Uncategorized Published - 18 April, 2016    By - Dr Clemens
The Effect of Preoperative Gabapentin on Postoperative Nausea and Vomiting: A Meta-Analysis

Anesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 976–985 AUTHORS: Grant, Michael C. MD et al BACKGROUND: Preoperative gabapentin has been shown to improve postoperative pain and limit reliance on opioid analgesia. On the basis of an alternative mechanism, our group investigated the ability of preoperative gabapentin to prevent postoperative […]

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Uncategorized Published - 18 April, 2016    By - Dr Clemens
The Effects of Ketamine on Cognitive Function in Elderly Patients Undergoing Ophthalmic Surgery: A Pilot Study

Anesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 969–975 AUTHORS: Rascón-Martínez, Dulce M. MD et al BACKGROUND: Acute postoperative cognitive dysfunction is characterized by neurocognitive dysfunction and confusion. In this study, we compared the cognitive status of a geriatric population undergoing ophthalmic surgery, as assessed by the Short Portable Mental […]

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Uncategorized Published - 18 April, 2016    By - Dr Clemens
Discordance in Grading Methods of Aortic Stenosis by Pre-Cardiopulmonary Bypass Transesophageal Echocardiography

Anesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 953–958 AUTHORS: Whitener, George MD et al BACKGROUND: Current guidelines define severe aortic valve stenosis (AS) as an aortic valve area (AVA) ≤1.0 cm2 by the continuity equation and mean gradient (ΔPm) ≥ 40 mm Hg. However, these measurements can be discordant when […]

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Uncategorized Published - 18 April, 2016    By - Dr Clemens
Lung Perfusion and Ventilation During Cardiopulmonary Bypass Reduces Early Structural Damage to Pulmonary Parenchyma

Anesthesia & Analgesia: April 2016 – Volume 122 – Issue 4 – p 943–952 AUTHORS: Claudia Regina MD, PhD et al BACKGROUND: It is unclear whether maintaining pulmonary perfusion and ventilation during cardiopulmonary bypass (CPB) reduces pulmonary inflammatory tissue injury compared with standard CPB where the lungs are not ventilated and are minimally perfused. In […]

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