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Researchers have found a link between dry eye and chronic pain syndromes — a finding that suggests that a new paradigm is needed for diagnosis and treatment to improve patient outcomes. “Our study indicates that some patients with dry eye have corneal somatosensory pathway dysfunction and would be better described as having neuropathic ocular pain,” […]
Read MoreMethylnaltrexone, a peripherally acting μ-opioid receptor (MOR) antagonist, may play a role in slowing tumor progression, new research has found. According to the study, methylnaltrexone influenced cancer progression and prolonged survival in patients with advanced cancer, suggesting that the MOR antagonist may be an important therapeutic target. “Our data suggest that methylnaltrexone used in advanced […]
Read MoreAn Italian study has found a linear correlation between the presence of acute pain within the first few hours of surgery and postoperative pain persisting for as long as six months afterward. The researchers hypothesized that anesthetic technique, including regional approaches, may influence the development and prevention of persistent postoperative pain. “Our goal was to […]
Read MoreDespite being an important part of clinical practice for more than five decades, the American Society of Anesthesiologists (ASA) physical status classification system occasionally is criticized for its subjective nature, a trait that can lead to inconsistent assignments among health care professionals. This problem can be ameliorated, a recent study has found, with the use […]
Read MoreBMC Anesthesiol. 2015;15(120) Authors: Øivind Jans et al Background: Intact orthostatic blood pressure regulation is essential for early mobilization after surgery. However, postoperative orthostatic hypotension and intolerance (OI) may delay early ambulation. The mechanisms of postoperative OI include impaired vasopressor responses relating to postoperative autonomic dysfunction. Thus, based on a previous study on haemodynamic responses during mobilization […]
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