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New research points to a specific gene that may explain why patients show varied responses to taking methadone. Interview with Evan D. Kharasch, MD, PhD Prescribing safe, effective dosages of methadone can be a serious clinical challenge for practitioners. A patient’s specific genetic makeup can significantly effect how the drug is metabolized—increasing the risk of […]
Read MoreEnhanced recovery after surgery (ERAS) pathways have been shown to improve clinical outcomes, reduce hospital length of stay (LOS) and reduce cost, with likely no increased risk for readmissions. However, as Andrew Gorlin, MD, of the Department of Anesthesiology at Mayo Clinic in Phoenix, explained at the 2016 American Society of Anesthesiologists Practice Management meeting, […]
Read MoreThe brain fog and clouded sensorium that follow a night call have long been accepted as part of the job by most anesthesiologists, but partial sleep deprivation significantly alters various aspects of mood and may ultimately affect the quality of patient care, a study has found. “It’s a given that residents work hours and hours, […]
Read MoreAuthors: Paul S. Myles, M.B.B.S., M.P.H., M.D. et al Anesthesiology published on 5 2016. Background: Several quality of recovery (QoR) health status scales have been developed to quantify the patient’s experience after anesthesia and surgery, but to date, it is unclear what constitutes the minimal clinically important difference (MCID). That is, what minimal change in score would […]
Read MoreCreating an analgesic devoid of unwanted side effects may seem like a pipe dream, but new research into analogs derived from natural compounds in the body have made bold progress. Developing a pain treatment that can provide effective analgesia and avoid unwanted side effects still stands as the holy grail of pain pharmacology, but researchers […]
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