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Uncategorized Published - 24 November, 2015    By - Dr Clemens
Major Adverse Events and Relationship to Nil per OsStatus in Pediatric Sedation/Anesthesia Outside the Operating Room: A Report of the Pediatric Sedation Research Consortium

Authors: Michael L. Beach, MD, PhD, et al Anesthesiology published on 11 2015. Background: Studies that have attempted to define the incidence of aspiration or pulmonary complications during sedation/anesthesia of children with respect to nil per os (NPO) status or other factors are difficult because of the relatively infrequent rate of these complications. Methods: The Pediatric Sedation Research Consortium consists of […]

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Uncategorized Published - 24 November, 2015    By - Dr Clemens
Patient-controlled Analgesia with Target-controlled Infusion of Hydromorphone in Postoperative Pain Therapy

Authors: Christian Jeleazcov MD. M.Sc, et al Anesthesiology published on 11 2015 Background: Patient-controlled analgesia (PCA) is a common method for postoperative pain therapy, but it is characterized by large variation of plasma concentrations. PCA with target-controlled infusion (TCI-PCA) may be an alternative. In a previous analysis, the authors developed a pharmacokinetic model for hydromorphone. In this secondary […]

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Uncategorized Published - 24 November, 2015    By - Dr Clemens
Long-term Survival for Patients Undergoing Volatile versus IV Anesthesia for Cancer Surgery: A Retrospective Analysis

Authors: Timothy J. Wigmore, MA, FRCA, FFCM, FFICM FCICM et al Anesthesiology published on 11 2015. Background: Surgical resection remains the best option for long-term survival in many solid tumors. Surgery can, however, lead to tumor cell release into the circulation. Data have suggested differential effects of anesthetic agents on cancer cell growth. This retrospective analysis investigated the […]

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Uncategorized Published - 23 November, 2015    By - Dr Clemens
Naloxone Nasal Spray Approved for Opioid Overdose

The FDA has approved a nasal spray version of naloxone hydrochloride (marketed as Narcan) to stop or reverse opioid overdose. The drug was previously approved only as an injection; the new version, says the agency, is both easier for first responders to administer and eliminates the risk for needlestick contamination. The drug is indicated for […]

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Uncategorized Published - 23 November, 2015    By - Dr Clemens
Ultrasound-Guided Peripheral IV Access in the Hands of Nurses’ Aides

Authors: McCarthy ML et al., Ann Emerg Med 2015 Oct 13; A large trial shows that ultrasound helps with moderate or difficult anticipated IV access when lines are placed by emergency department technicians. Multiple small studies since 2005 have shown that ultrasound guidance improves success of peripheral intravenous (IV) line placement when access is difficult. These researchers […]

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