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Br J Anaesth. 2016;116(3):339-349 Authors: P. Marik et al Abstract Aggressive fluid resuscitation to achieve a central venous pressure (CVP) greater than 8 mm Hg has been promoted as the standard of care, in the management of patients with severe sepsis and septic shock. However recent clinical trials have demonstrated that this approach does not […]
Read MoreThis is for our readers who treat pain clinic so they often prescribe drugs. An Illinois-based psychiatrist has been sentenced to 9 months in federal prison and ordered to pay nearly $600,000 for accepting hundreds of thousands of dollars in pharmaceutical industry kickbacks. Michael J. Reinstein, MD, was convicted of accepting payments from industry in […]
Read MoreAuthors: Siracuse BL et al JAMA Surg. 2016 Mar 9. Study Summary In this study, investigators analyzed retrospective discharge data on 268,518 patients from New York and California (ie, the derivation cohort) and 153,560 patients from Florida and Washington (ie, the validation cohort) who underwent total hip replacement during 2006-2011.The goal was to determine the […]
Read MoreAnesthesia & Analgesia: April 2016 AUTHORS: Hayes, Jason MD et al BACKGROUND: Bolus administration of opioids via a patient-controlled analgesia (PCA) device is widely used in the postoperative pediatric population. PCA devices have been shown to provide superior analgesia and greater patient satisfaction compared with intermittent administration. Studies comparing the efficacy of PCA with and […]
Read MoreTherapy with supervised hydromorphone (multiple brands) injections shows noninferiority to therapy with diacetylmorphine hydrochloride (the active ingredient in heroin) in the treatment of severe opioid dependence, suggesting a potentially effective alternative treatment for severe, treatment-refractory patients, new research shows. “Our study shows that a licensed medication, hydromorphone, is as good as diacetylmorphine at reducing the […]
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