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Anesthesiology Published - 26 August, 2026    By - Dr Clemens
Vasopressin Versus Norepinephrine As First-Line Vasopressor Therapy for Vasoplegic Shock Following Cardiac Surgery

Authors: Divya A, Dalal N, McKendry G, et al. Cureus 18(7): e112528. doi:10.7759/cureus.112528 Abstract Vasoplegic shock following cardiac surgery is associated with significant morbidity. While norepinephrine is recommended as first-line therapy, vasopressin has been proposed as an alternative due to catecholamine-independent mechanisms. Comparative evidence in postcardiac surgery populations remains limited. We conducted a systematic review […]

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Anesthesiology Published - 26 August, 2026    By - Dr Clemens
Granisetron for Postoperative Nausea and Vomiting Prophylaxis in Microvascular Decompression Despite Prominent Non-serotonergic Emetic Pathways

Authors: Oishi H, Kato T, Hagiwara N, et al. Cureus 18(7): e112568. doi:10.7759/cureus.112568 Background Microvascular decompression (MVD) is associated with a high incidence of postoperative nausea and vomiting (PONV). Unlike in general surgery, where PONV is predominantly serotonin-mediated, MVD additionally activates non-serotonergic emetic mechanisms, including vestibular stimulation and direct brainstem perturbation. Whether selective 5-HT₃ receptor […]

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Anesthesiology Published - 26 August, 2026    By - Dr Clemens
Perioperative Multidisciplinary Collaboration Is Essential for Successful Complex Multi-staged Oncological Surgical Procedures in Military Treatment Facilities

Authors: Kane T M, Russo C M, Chirdon P, et al. Cureus 18(7): e112650. doi:10.7759/cureus.112650 Abstract Although giant cell tumors are generally benign, locally aggressive growth can cause profound pathologic tissue destruction and, in some cases, transform into metastatic neoplasms. Here, we present the case of a 37-year-old female with a previously decompressed giant cell […]

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Anesthesiology Published - 26 August, 2026    By - Dr Clemens
Anesthetic Management of a Pediatric Patient With CTNNB1-Related Neurodevelopmental Disorder

Authors: Rocha A, Cardante Santos C, Alves P, et al. Cureus 18(7): e112723. doi:10.7759/cureus.112723 Abstract CTNNB1-related neurodevelopmental disorder with spastic diplegia and visual defect (NEDSDV) is a rare genetic condition characterized by developmental delay, axial hypotonia, peripheral spasticity, and ophthalmologic abnormalities. Due to its phenotypic overlap with bilateral spastic cerebral palsy, NEDSDV may be underdiagnosed, […]

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Anesthesiology Published - 26 August, 2026    By - Dr Clemens
Anesthetic Considerations in a High-Risk Pregnant Patient With Myelomeningocele and Urosepsis Undergoing Emergent Surgery

Authors: Sievers M, Meral R, Anderson D Cureus 18(7): e112535. doi:10.7759/cureus.112535 Abstract The patient was a pregnant 30-year-old gravida 6, para 0 (G6P0) woman at 22 weeks and four days (22w4d) with myelomeningocele and neurogenic bladder who presented with progressive pain, fevers, chills, and transaminitis concerning for urosepsis requiring emergent cystolithalopaxy. Preoperative evaluation identified marked lower-extremity […]

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