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Uncategorized Published - 2 September, 2016    By - Dr Clemens
Lipid Emulsion in Local Anesthetic Toxicity: Long-winded, Rude, and Right

Authors: Martyn Harvey, M.D., F.A.C.E.M. et al    Commentary: Effect of Intralipid® on the Dose of Ropivacaine or Levobupivacaine Tolerated by Volunteers: A Clinical and Pharmacokinetic Study Anesthesiology 9 2016, Vol.125, 451-453. LORD Cyril Asquith, son of a British Prime Minister, and himself an English Law Lord, once remarked “A Judge of the first instance should be […]

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Uncategorized Published - 2 September, 2016    By - Dr Clemens
Good News: But Why Is the Incidence of Postoperative Ischemic Optic Neuropathy Falling?

Author: Michael M. Todd, M.D. Commentary: Perioperative Visual Loss in Spine Fusion Surgery: Ischemic Optic Neuropathy in the United States from 1998 to 2012 in the Nationwide Inpatient Sample Anesthesiology 9 2016, Vol.125, 445-448. THE first description of postoperative visual loss (POVL) in Medline is from 1950. Cases appeared sporadically over the next 30 to 40 yr, mostly […]

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Uncategorized Published - 2 September, 2016    By - Dr Clemens
Oxygen Therapy: When Is Too Much Too Much?

Commentary: A Multicenter, Randomized, Controlled Phase IIb Trial of Avoidance of Hyperoxemia during Cardiopulmonary Bypass Authors: Shahzad Shaefi, M.D. et al Anesthesiology 9 2016, Vol.125, 449-450. THERE are approximately 300,000 cardiac surgical procedures annually utilizing cardiopulmonary bypass (CPB) in the United States.  The delivery of oxygen has been a cornerstone of anesthesia practice, with titration of oxygen therapy to […]

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Uncategorized Published - 1 September, 2016    By - Dr Clemens
Which Anesthesia Regimen Is Best to Reduce Morbidity and Mortality in Lung Surgery?: A Multicenter Randomized Controlled Trial

Authors: Beatrice Beck-Schimmer, M.D. et al Anesthesiology 8 2016, Vol.125, 313-321. Background: One-lung ventilation during thoracic surgery is associated with hypoxia–reoxygenation injury in the deflated and subsequently reventilated lung. Numerous studies have reported volatile anesthesia–induced attenuation of inflammatory responses in such scenarios. If the effect also extends to clinical outcome is yet undetermined. We hypothesized that volatile […]

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Uncategorized Published - 1 September, 2016    By - Dr Clemens
Changes in Brain Resting-state Functional Connectivity Associated with Peripheral Nerve Block: A Pilot Study

Authors: M. Stephen Melton, M.D. et al Anesthesiology 8 2016, Vol.125, 368-377 Background: Limited information exists on the effects of temporary functional deafferentation (TFD) on brain activity after peripheral nerve block (PNB) in healthy humans. Increasingly, resting-state functional connectivity (RSFC) is being used to study brain activity and organization. The purpose of this study was to test […]

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