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Authors: Mathieu Raux, M.D., Ph.D. et al Anesthesiology 3 2017, Vol.126, 522-533. Background: Initial blood lactate and base deficit have been shown to be prognostic biomarkers in trauma, but their respective performances have not been compared. Methods: Blood lactate levels and base deficit were measured at admission in trauma patients in three level 1 trauma centers. This […]
Read MoreAuthors: Leanne Clifford, B.M. et al Anesthesiology 3 2017, Vol.126, 409-418 Background: Transfusion-associated circulatory overload remains underappreciated in the perioperative environment. The authors aimed to characterize risk factors for perioperative transfusion-associated circulatory overload and better understand its impact on patient-important outcomes. Methods: In this case–control study, 163 adults undergoing noncardiac surgery who developed perioperative transfusion-associated circulatory overload were […]
Read MoreAuthors: Michael R. Mathis, M.D. et al Anesthesiology 3 2017, Vol.126, 450-460. Background: Patients with left ventricular assist devices presenting for noncardiac surgery are increasingly commonplace; however, little is known about their outcomes. Accordingly, the authors sought to determine the frequency of complications, risk factors, and staffing patterns. Methods: The authors performed a retrospective study at their […]
Read MoreAuthors: Rhodes A et al., Intensive Care Med 2017 Jan 18; This revision of the 2012 guidelines focuses on early management in adults. Sponsoring Organizations: Surviving Sepsis Campaign, Society of Critical Care Medicine, and European Society of Intensive Care Medicine Target Population: Clinicians who care for adult patients with sepsis and septic shock in a hospital setting. Background and […]
Read MoreThe Institute for Safe Medicine Practices reviewed 12 months of FDA data and identified hundreds of cases of acute liver failure in patients taking direct-acting antivirals for hepatitis C. In October, the FDA announced that it was adding a boxed warning to the labels of direct-acting antivirals after identifying 24 cases of hepatitis B reactivation. […]
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