Authors: Girish P. Joshi, M.B.B.S., M.D. et al Anesthesiology December 2024, Vol. 141, 1208–1209. To the Editor: There is an exponential increase in the use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in recent years due to their numerous clinical benefits. However, GLP-1RAs delay gastric emptying with recent reports of aspiration of gastric contents during sedation and general […]
GABAergic neurons in the central amygdala promote emergence from isoflurane anesthesia in mice
Authors: Jin-Sheng Zhang, M.S. et al Anesthesiology October 2024. Background Recent evidence indicates that general anesthesia and sleep-wake behavior share some overlapping neural substrates. GABAergic neurons in the central amygdala (CeA) have a high firing rate during wakefulness and play a role in regulating arousal-related behaviors. The objective of this study is to investigate whether […]
The effect of intraoperative midazolam on postoperative delirium in older surgical patients
Authors: Hao Li, M.D., Ph.D. et al Anesthesiology October 2024. Background Midazolam is a short-acting benzodiazepine frequently used in the perioperative setting. This study aimed to investigate the potential impact of intraoperative midazolam on postoperative delirium (POD) in older patients undergoing non-cardiac surgery. Methods This study included patients aged ≥ 65 years who received general […]
Chewing gum to treat postoperative nausea and vomiting in female patients
Authors: Jai N. Darvall, Ph.D., F.A.N.Z.C.A. et al Anesthesiology October 2024. Background Postoperative nausea and vomiting (PONV) is common after general anesthesia, with consequences for patient outcomes, satisfaction with care and healthcare costs. Our aim was to compare a new treatment, chewing gum, with a widely-used intravenous agent, ondansetron, to treat PONV in female patients […]
Discover The Best Anesthesiologist Opportunity in New Mexico
We are seeking a dedicated anesthesiologist to join our all-anesthesiologist group. Our team will consist of 4 full-time providers and 1 for vacation relief, managing 3 operating rooms. Position Highlights: Zero call for 3 weeks, followed by 1 week of call without daytime work only call after 7 PM therefore you may not work the […]
A Great Anesthesiologist Opportunity in Gadsden AL
We are seeking a dedicated anesthesia care team to join our new anesthesia care team contract at Riverview Regional Medical Center. Gadsden is a town of over 100,000 people that is located 1 hour from Birmingham AL and 2 hours from Atlanta GA. Position Highlights: Anesthesiologist call is 1:3 Competitive salary of $500,000 plus benefits. […]
Ultrasound guided transcutaneous phrenic nerve stimulation in critically ill patients: a new method to evaluate diaphragmatic function
Authors: Mathieu Capdevila, M.D., Ph.D. et al Anesthesiology October 2024. d Background Diaphragm dysfunction is common in intensive care unit and associated with weaning failure and mortality. Diagnosis gold standard is the transdiaphragmatic or tracheal pressure induced by magnetic phrenic nerve stimulation. However, the equipment is not commonly available and requires specific technical skills. We […]
Restrictive versus Decision Support Guided Fluid Therapy during Major Hepatic Resection Surgery
Authors: Sean Coeckelenbergh, M.D., Ph.D. et al Anesthesiology November 2024, Vol. 141, 881–890. Background Fluid therapy during major hepatic resection aims at minimizing fluids during the dissection phase to reduce central venous pressure, retrograde liver blood flow, and venous bleeding. This strategy, however, may lead to hyperlactatemia. The Acumen assisted fluid management system uses novel decision […]
Cannabis Use and Inhalational Anesthesia Administration in Older Adults
Authors: Ruba Sajdeya, M.D., Ph.D. et al Anesthesiology November 2024, Vol. 141, 870–880. Background Cannabis use is associated with higher intravenous anesthetic administration. Similar data regarding inhalational anesthetics are limited. With rising cannabis use prevalence, understanding any potential relationship with inhalational anesthetic dosing is crucial. Average intraoperative isoflurane or sevoflurane minimum alveolar concentration equivalents between older […]
Correction of Trauma-induced Coagulopathy by Goal-directed Therapy
Authors: Charlotte Lindsay, M.Sc. et al Anesthesiology November 2024, Vol. 141, 904–912. Background Trauma hemorrhage induces a coagulopathy with a high associated mortality rate. The Implementing Treatment Algorithms for the Correction of Trauma Induced Coagulopathy (ITACTIC) randomized trial tested two goal-directed treatment algorithms for coagulation management: one guided by conventional coagulation tests and one by viscoelastic […]