AUTHORS: Fislage, Marinus PhD student et al Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 136-142 BACKGROUND: Previous studies suggest a role of the thalamus in cognitive function, while others implicate it as a central effect site of anesthetics. Yet, its role in postoperative neurocognition in the aging brain remains uncertain. […]
Read MoreAUTHORS: Jokinen, Johan D. V. MD et al Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 100-109 BACKGROUND: New-onset postoperative atrial fibrillation (POAF) is associated with several cardiovascular complications and higher mortality. Several pathophysiological processes such as hypoxia can trigger POAF, but these are sparsely elucidated, and POAF is often asymptomatic. […]
Read MoreAUTHORS: Patrick L. Purdon, PhD et al ASA Monitor May 2022, Vol. 86, 1–9. The brain under anesthesia is a marvel to behold. Although the electroencephalogram (EEG) is not a routine part of clinical anesthesia care, there is growing evidence that readily visible changes in the anesthesia-induced EEG are intimately linked to perioperative brain health. Induction […]
Read MoreAUTHORS: Otsuki, Sachiko MD, PhD et al Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 128-135 BACKGROUND: Malignant hyperthermia (MH) is an inherited muscle disorder induced by volatile anesthetics and depolarizing muscle relaxants. While the incidence of MH is high in young, there are few reports on the clinical features of […]
Read MoreAUTHORS: Du, Austin L. BS et al Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 118-127 BACKGROUND: The rise in obesity in the United States, along with improvements in antiviral therapies, has led to an increase in the number of obese patients receiving liver transplants. Currently, obesity is a relative contraindication […]
Read MoreAUTHORS: Hsu, Wan-Ting MS et al Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 110-117 BACKGROUND: Aspirin has anti-inflammatory and antiplatelet activities and directly inhibits bacterial growth. These effects of aspirin may improve survival in patients with sepsis. We retrospectively reviewed a large national health database to test the relationship between […]
Read MoreAUTHORS: Yang, Mikyung MD, PhD et al Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 91-99 BACKGROUND: A high fraction of inspired oxygen (Fio2) is administered during one-lung ventilation (OLV). However, a high Fio2 is not physiologic and may lead to various complications. We hypothesized that continuous titration of Fio2 using the oxygen […]
Read MoreAUTHORS: Greiwe, Gillis MD et al Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 71-78 BACKGROUND: Cardiac output (CO) is a key determinant of oxygen delivery, but choosing the optimal method to obtain CO in pediatric patients remains challenging. The pressure recording analytical method (PRAM), implemented in the MostCareUp system (Vygon), […]
Read MoreAUTHORS: Wu, Zhijie MD et al Anesthesia & Analgesia: July 2022 – Volume 135 – Issue 1 – p 62-70 BACKGROUND: CO2 has anesthetic potency and effectively influences the circulatory system. We investigated the effects of Etco2 on the minimum alveolar concentration of sevoflurane that blunts the adrenergic response to surgical incision (MAC-BAR) in patients undergoing radical surgery […]
Read MoreAuthor: Ferdinand Lali, Ph.D. MedicalNewsToday A new observational study suggests that intravenous administration of the anesthetic agent lidocaine could help alleviate pain in individuals hospitalized with hard-to-treat chronic migraines. Nearly 88% of chronic migraine patients receiving intravenous lidocaine during hospitalization showed a reduction in pain intensity at discharge. This study paves the way for randomized […]
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