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Author: Phillip E. Vlisides, M.D. Anesthesiology July 2024, Vol. 141, 194–195. In Reply: We thank Mr. Kubo and Dr. Hosokawa for their interest in our study. Perioperative neurocognitive disorders are a major public health issue, and advancing our neurobiologic understanding of these impairments represents an important step toward prevention and management. Our team welcomes the opportunity […]
Read MoreAuthors: Akira Kubo, M.S.; Koji Hosokawa, M.D., Ph.D. Anesthesiology July 2024, Vol. 141, 193–194. To the Editor: We read with great interest the recent article by Vlisides et al. The authors demonstrated that while intraoperative cortical connectivity measured using 16-channel electroencephalography (EEG) was not linked to postoperative cognitive function, global theta activity was associated with postoperative delirium. The […]
Read MoreAuthors: Akihiro Suzuki, M.D., Ph.D. et al Anesthesiology July 2024, Vol. 141, 161–162. Displacement of the epiglottis, also known as epiglottic folding, downfolding, or prolapse, is an unexpected complication associated with tracheal intubation and supraglottic airway device insertion. Recent advancements in endoscopic technology and the widespread use of video/optical devices, such as videolaryngoscopes, have brought this […]
Read MoreEndovascular thrombectomy plus medical care versus medical care alone for large ischaemic stroke: 1-year outcomes of the SELECT2 trial. Lancet 2024; 403:731–40. PMID: 38346442. Author: Jamie Sleigh, M.D. Anesthesiology July 2024, Vol. 141, A13–A15. Although many trials have shown improved early recovery in patients with large ischemic stroke treated with endovascular thrombectomy, it is unknown whether […]
Read MoreAuthors: Yujie Wu, M.M. et al Anesthesiology July 2024, Vol. 141, 56–74. Background Stimulation of the paraventricular thalamus has been found to enhance anesthesia recovery; however, the underlying molecular mechanism by which general anesthetics modulate paraventricular thalamus is unclear. This study aimed to test the hypothesis that the sodium leak channel (NALCN) maintains neuronal activity in […]
Read MoreAuthors: Kirti Sahu, M.D. et al Anesthesiology July 2024, Vol. 141, 159–160. A 15-YR-OLD boy with dysphonia and difficulty clearing secretions due to a glottic web underwent an endoscopic excision and Gore-Tex (W. L. Gore & Associates, Inc., USA) laryngeal keel placement (fig. 1). Laryngeal keels are used to achieve and maintain separation at the anterior […]
Read MoreAuthors: Laurent G. Glance, M.D. et al Anesthesiology July 2024, Vol. 141, 116–130. Background The objective of this study was to examine insurance-based disparities in mortality, nonhome discharges, and extracorporeal membrane oxygenation utilization in patients hospitalized with COVID-19. Methods Using a national database of U.S. academic medical centers and their affiliated hospitals, the risk-adjusted association between […]
Read MoreAuthors: Irene Suárez-Pereira, Ph.D. et al Anesthesiology July 2024, Vol. 141, 131–150. Background Dynamic changes in neuronal activity and in noradrenergic locus coeruleus (LC) projections have been proposed during the transition from acute to chronic pain. Thus, the authors explored the cellular cFos activity of the LC and its projections in conjunction with spontaneous pain-like behavior […]
Read MoreAuthors: Nikolaos J. Skubas, M.D., D.Sc., F.A.C.C., F.A.S.E. et al Anesthesiology July 2024, Vol. 141, 10–12. “[A] multicomponent assessment of dyspnea is important in awake venoarterial ECMO patients.” In this issue of Anesthesiology, Bureau et al. delineate the characteristics and treatment of dyspnea in a unique cohort of patients, namely spontaneously breathing patients with cardiogenic shock receiving modest […]
Read MoreAuthor: Charles Emala, M.D. Anesthesiology July 2024, Vol. 141, A13–A15. Capillary oxygen regulates demand-supply coupling by triggering connexin40-meidated conduction: Rethinking the metabolic hypothesis. Proc Natl Acad Sci USA 2024; 121:e2303119121. PMID: 38349880. Tissue oxygen delivery requires localized sensing of oxygen demand that dictates upstream arteriolar dilation. Microvascular blood flow is closely matched to tissue oxygen requirements […]
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