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Authors: Ian Yuan, M.D., M.Eng. et al Anesthesiology August 2024, Vol. 141, 353–364. Background Unlike expired sevoflurane concentration, propofol lacks a biomarker for its brain effect site concentration, leading to dosing imprecision particularly in infants. Electroencephalography monitoring can serve as a biomarker for propofol effect site concentration, yet proprietary electroencephalography indices are not validated in infants. […]
Read MoreAuthors: Gamonmas Ekkapat, M.D. et al Anesthesiology August 2024, Vol. 141, 377–378. A 43-yr-old woman experienced acute respiratory failure with right ventricular dysfunction following a complex left pneumonectomy (fig. 1A) with cardiopulmonary bypass. She was intubated and mechanically ventilated. Fig. 1. (A) Chest x-ray showing patchy opacities at the right middle and lower lung zones along […]
Read MoreAuthors: Kim I. Albers-Warlé, M.D et al Anesthesiology August 2024, Vol. 141, 365–374. Background The number of trials investigating the effects of deep neuromuscular blockade (NMB) on surgical conditions and patient outcomes is steadily increasing. Consensus on which surgical procedures benefit from deep NMB (a posttetanic count [PTC] of 1 to 2) and how to implement […]
Read MoreAnesthesiology August 2024, Vol. 141, A13–A15. Clonal hematopoiesis of indeterminate potential is associated with acute kidney injury. Nat Med 2024; 30:810–7. PMID: 38454125. Acute kidney injury after hypoperfusion is common and it has a higher occurrence in older patients but has not previously been clearly associated with genetic risk factors. Clonal hematopoiesis of indeterminate potential is […]
Read MoreAuthors: Jamie W. Sleigh, M.D.; Philip G. Morgan, M.D. Anesthesiology August 2024, Vol. 141, 214–216. “[T]he confusing results of GWAS do suggest that the mechanisms of how the genome manifests expression in a living human may be more subtle and complex than the traditionally taught paradigm of DNA–mRNA–tRNA–protein.” Practicing clinicians spend their days managing the variability in […]
Read MoreWe are seeking a dedicated anesthesiologist to join our all-anesthesiologist group. Our team will consist of 4 full-time providers and 1 for vacation relief, managing 3 operating rooms. Position Highlights: Zero call for 3 weeks, followed by 1 week of call without daytime work only call after 7 PM therefore you may not work the […]
Read MoreAuthors: Melodie Fanay Boko, B.Sc. et al Anesthesiology August 2024, Vol. 141, 286–299. Background The amount of same-day surgery has increased markedly worldwide in recent decades, but there remains limited evidence on chronic postsurgical pain in this setting. Methods This study assessed pain 90 days after ambulatory surgery in an international, multicenter prospective cohort study of […]
Read MoreAuthors: Vincent So, M.D. et al Anesthesiology August 2024, Vol. 141, 313–325. Background Adenotonsillectomy and tonsillectomy (referred to as tonsillectomy hereafter) are common pediatric surgeries. Postoperative complications include hemorrhage requiring surgery (2 to 3% of cases) and pain. Although nonsteroidal anti-inflammatory drugs are commonly administered for postsurgical pain, controversy exists regarding bleeding risk with cyclooxygenase-1 inhibition […]
Read MoreAuthor: Aaron TallentMedCentral AI tools can help medical practices identify at-risk behavior among staff. In the first season of True Detective, detective Rust Cohle (Matthew McConaughey) enters a police evidence room in the 1990s and walks out with a brick of cocaine, saying, “They really need a better system for this.” While law enforcement has done […]
Read MoreAnesthesiology September 2024, Vol. 141, A13–A15. Trial of early minimally invasive removal of intracerebral hemorrhage. N Engl J Med 2024; 390:1277–89. PMID: 38598795. It is widely accepted that the evacuation of acute supratentorial intracerebral hemorrhages does not improve patient outcomes. However, recent advances in minimally invasive neurosurgical techniques (such as trans-sulcal parafascicular surgery) enable effective hematoma […]
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