Author: Dr Clemens

Uncategorized Published - 2 July, 2024    By - Dr Clemens
Science, Medicine, and the Anesthesiologist

The central renin-angiotensin system: A genetic pathway, functional decoding, and selective target engagement characterization in humans. Proc Natl Acad Sci U S A 2024; 121:e2306936121. PMID: 38349873. Author: Charles Emala, M.D. Anesthesiology July 2024, Vol. 141, A13–A15. The peripheral renin angiotensin system (RAS) is a well-characterized hormonal system classically understood to regulate cardiovascular and renal functions, […]

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Uncategorized Published - 1 July, 2024    By - Dr Clemens
Increasing Sweep Gas Flow Reduces Respiratory Drive and Dyspnea in Nonintubated Venoarterial Extracorporeal Membrane Oxygenation Patients

Authors: Côme Bureau, M.D., Ph.D. et al  Anesthesiology July 2024, Vol. 141, 87–99. Background Data on assessment and management of dyspnea in patients on venoarterial extracorporeal membrane oxygenation (ECMO) for cardiogenic shock are lacking. The hypothesis was that increasing sweep gas flow through the venoarterial extracorporeal membrane oxygenator may decrease dyspnea in nonintubated venoarterial ECMO patients […]

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Uncategorized Published - 1 July, 2024    By - Dr Clemens
Thinking Beyond the OR: Preventing Delirium

Authors: Ashish Agrawal, MD et al  ASA Monitor October 2023, Vol. 87, 35. Delirium is likely the most well-known perioperative cognitive disorder. Delirium, an acute and fluctuating alteration in the level of consciousness and attention, has significant consequences for patients, families, and the health care system. The incidence of delirium is associated with increased mortality, cognitive […]

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Uncategorized Published - 1 July, 2024    By - Dr Clemens
Prospects for pain medicine in 4 elements

Author: Carly Behm Becker’s Spine Review Pain medicine and spine care can work in tandem, and their success will involve four key elements, according to one spine surgeon. “Pain medicine is navigating an era of unprecedented progress, and one of the key driving forces behind this evolution is the collaborative relationship between pain specialists and […]

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Uncategorized Published - 1 July, 2024    By - Dr Clemens
A New Psychotherapeutic ‘Gold Standard’ for Chronic Pain?

Author: Alicia Ault Medscape Anesthesiology A single course of treatment with emotional awareness and expression therapy (EAET) was associated with a significantly greater reduction in chronic pain severity than cognitive-behavioral therapy (CBT), the current psychotherapeutic gold standard, a new study suggested. Two thirds of the patients who received EAET reported at least a 30% reduction […]

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Uncategorized Published - 1 July, 2024    By - Dr Clemens
Science, Medicine, and the Anesthesiologist

Author: Beatrice Beck-Schimmer Anesthesiology July 2024, Vol. 141, A13–A15. Individualized treatment effects of oxygen targets in mechanically ventilated critically ill adults. JAMA 2024; 331:1195–204. PMID: 38501205. Based on data from randomized trials, no oxygenation targets are known to affect patient outcome. Also, oxygenation targets specific to a patient’s characteristics have not been reported. This study was […]

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Uncategorized Published - 28 June, 2024    By - Dr Clemens
Using the Spectrogram to Interpret Electroencephalographic (EEG) Waveforms

Authors: Seyed A. Safavynia, MD, PhD; Shobana Rajan, MD, FASA ASA Monitor May 2024, Vol. 88, 28–29. Electroencephalographic (EEG) monitoring has become increasingly commonplace in the anesthesiologist’s practice since the Bispectral IndexTM (BISTM) Monitor (Medtronic) was approved by the U.S. Food and Drug Administration (FDA) in 1996 for monitoring anesthetic depth. Today, several other intraoperative EEG devices exist, […]

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Uncategorized Published - 28 June, 2024    By - Dr Clemens
Evaluate Extubation in Neurosurgical Patients: Reply

Authors: Shan-Shan Xu, M.D.; Linlin Zhang, M.D., Ph.D.; Jian-Xin Zhou, M.D., Ph.D. Anesthesiology July 2024, Vol. 141, 196–197. In Reply: WE would like to thank Yamazaki and Hosokawa for their interest in our article.  The authors highlight four concerns about using the Swallowing, Tongue protrusion, Airway protection reflected by spontaneous and suctioning cough, and Glasgow coma scale Evaluation (STAGE) […]

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Uncategorized Published - 28 June, 2024    By - Dr Clemens
Evaluate Extubation in Neurosurgical Patients: Comment

Authors: Yukiko Yamazaki, M.D.; Koji Hosokawa, M.D., Ph.D. Anesthesiology July 2024, Vol. 141, 195–196. To the Editor: We read with great interest the recent article by Xu et al. that discusses how the Swallowing, Tongue protrusion, Airway protection reflected by spontaneous and suctioning cough, and Glasgow coma scale Evaluation (STAGE) score of neurologic patients may predict the success of […]

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Uncategorized Published - 28 June, 2024    By - Dr Clemens
Rethinking Coagulation Activation during Extracorporeal Membrane Oxygenation: Insights from the Case of Mr. Hageman

Authors: Kenichi A. Tanaka, M.D., M.Sc. et al  Anesthesiology July 2024, Vol. 141, 7–9. “… their findings … may have clinical implications for understanding ECMO-related bleeding. While they did not conclusively demonstrate a causal relationship, their data suggest that patients who bled had significantly elevated signals of contact activation based on biomarkers.” Blood surface interfacing that […]

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