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Edited by David G. Fairchild, MD, MPH Mindfulness-based stress reduction (MBSR) and cognitive behavioral therapy (CBT) are associated with reduced pain and disability in patients with chronic low back pain, suggests a JAMA study. Researchers randomized over 300 adults with moderate low back pain lasting at least 3 months to one of three 8-week options: MBSR, CBT, or […]
Read MoreEdited by David G. Fairchild, MD, MPH All immediate-release prescription opioids must now carry a boxed warning about the risks for abuse, addiction, and misuse associated with the painkillers, the FDA announced on Tuesday. The updates include the following: A warning that immediate-release opioids are intended to be taken every 4–6 hours and should only be […]
Read MoreAuthors: Yushi Yang, Ph.D. et al Anesthesiology 4 2016, Vol.124, 795-803. Background: Prefilled syringes (PFS) have been recommended by the Anesthesia Patient Safety Foundation. However, aspects in PFS systems compared with self-filled syringes (SFS) systems have never been explored. The aim of this study is to compare system vulnerabilities (SVs) in the two systems and understand the […]
Read MoreAuthors: Derryn A. Gargiulo, M.Pharm.Clin., Reg.Pharm.N.Z. et al Anesthesiology 4 2016, Vol.124, 785-794. Background: The aseptic techniques of anesthesiologists in the preparation and administration of injected medications have not been extensively investigated, but emerging data demonstrate that inadvertent lapses in aseptic technique may be an important contributor to surgical site and other postoperative infections. Methods: A prospective, open, […]
Read MoreKhandelwal N et al., Anesth Analg 2016 Feb 10; In this retrospective study, patients intubated in a semi-erect, head-forward position had lower rates of peri-intubation adverse events than those in a supine position. Desaturation and poor direct laryngeal views are two important factors leading to intubation failure. In the operating room (OR), direct laryngoscopy is easier when […]
Read MoreEdited by André Sofair, MD, MPH, and William E. Chavey, MD, MS Diclofenac, etoricoxib, and rofecoxib were associated with the greatest pain reduction for patients with knee or hip osteoarthritis, while acetaminophen was not superior to placebo, in a network meta-analysis in the Lancet. (Etoricoxib is not available in the U.S.; rofecoxib was withdrawn worldwide in 2004.) Researchers assessed […]
Read Moreby Erica L. Holland, MD; Carli D. Hoaglan, MD; Martha A. Carlstead, CRNA; Ryan P. Beecher, CRNA; Grete H. Porteous, MD Introduction Loss of electrical power in a hospital is a patient safety hazard that has been neglected in medical training and research.1,2 The technology-rich environment of the operating room (OR) puts patients at risk should […]
Read Moreby Karl E. Hammermeister, MD; Michael Bronsert, PhD; Joshua S. Richman, MD, PhD; and William G. Henderson, PhD Historical The earliest description of curare, a naturally occurring predecessor of the neuromuscular blocking agents commonly used today in anesthesia, has been attributed to Sir Walter Raleigh in his 1596 book, The Discoverie of the Large, Rich, and […]
Read Moreby Glenn Murphy, MD The Neuromuscular Research Group at Organon Newhouse Scotland (east of Glasgow) had been working on the development of fast-onset, short-acting, nondepolarizing steroidal neuromuscular blocking agents since the 1960s, which led to the development of pancuronium, vecuronium and rocuronium. Shortly after the launch of rocuronium, questions arose about a possible action of […]
Read MoreWhat Would You Expect If You Were the Patient? by Robert K. Stoelting, MD The Anesthesia Patient Safety Foundation (APSF) believes that residual neuromuscular blockade in the postoperative period is a patient safety hazard that could be addressed partially by better and consistent use of our qualitative standard train-of-four (TOF) nerve stimulator monitors, but will […]
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