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Authors: Glenn S. Murphy, M.D. etal Anesthesiology 10 2016, Vol.125, 611-614 BY the late 1980s, it was well recognized that undetected postoperative residual neuromuscular block (PRNB) was a common occurrence in most postanesthesia care units (PACUs).1–4 However, an editorial in 1989 noted that there was little, if any, objective evidence to validate the hypothesis that PRNB […]
Read MoreAuthors: M. Ruth Graham, M.D., F.R.C.P.(C). et al Anesthesiology 10 2016, Vol.125, 667-677 Background: Animal studies demonstrate general anesthetic (GA) toxicity in the developing brain. Clinical reports raise concern, but the risk of GA exposure to neurodevelopment in children remains uncertain. Methods: The authors undertook a retrospective matched cohort study comparing children less than 4 yr of age […]
Read MoreAuthors: Catherine M. Bulka, M.P.H. et al Anesthesiology 10 2016, Vol.125, 647-655. Background: Residual postoperative paralysis from nondepolarizing neuromuscular blocking agents (NMBAs) is a known problem. This paralysis has been associated with impaired respiratory function, but the clinical significance remains unclear. The aims of this analysis were two-fold: (1) to investigate if intermediate-acting NMBA use […]
Read MoreAnesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 402–410 AUTHORS: Moaveni, Daria M. MD et al Over the past 40 years, the success of organ transplantation has increased such that female solid organ transplant recipients are able to conceive and carry pregnancies successfully to term. Anesthesiologists are faced with the […]
Read MoreAnesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 396–401 AUTHORS: Frölich, Michael A. MD et al BACKGROUND: Hormonal action has been implicated as a possible mechanism for pregnancy-induced analgesia. Previous investigators have reported an increase in heat pain tolerance during labor compared with nonpregnant controls and postulated it was because […]
Read MoreAnesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 371–381 AUTHORS: Xu, Jing-Yuan MD et al BACKGROUND: Whether early goal-directed therapy (EGDT) improves outcome in severe sepsis and septic shock remains unclear. We performed a meta-analysis of existing clinical trials to examine whether EGDT improved outcome in the resuscitation of adult […]
Read MoreAnesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 346–356 AUTHORS: Alian, Aymen A. MD et al BACKGROUND: Scoliosis surgery is often associated with substantial blood loss, requiring fluid resuscitation and blood transfusions. In adults, dynamic preload indices have been shown to be more reliable for guiding fluid resuscitation, but these […]
Read MoreAuthors: Eric C. Cheon, M.D. et al Anesthesiology published on September 15, 2016. Background: To date, the independent predictors and outcomes of unplanned postoperative intubation (UPI) in pediatric patients after noncardiac surgery are yet to be characterized. The authors aimed to identify the incidence and predictors of this event and evaluated the effect of this event on […]
Read MoreAnesthesia & Analgesia: August 2016 – Volume 123 – Issue 2 – p 311–325 AUTHORS: Djafarzadeh, Siamak PhD et al BACKGROUND: Remifentanil interferes with hepatic mitochondrial function. The aim of the present study was to evaluate whether hepatic mitochondrial function is affected by fentanyl, a more widely used opioid than remifentanil. METHODS: Human hepatoma HepG2 […]
Read MoreAnesthesia & Analge sia:August 2016 – Volume 123 – Issue 2 – p 283–289 AUTHORS: Zhang, Wei et al BACKGROUND: Postoperative atrial fibrillation (AF) is associated with increased morbidity, mortality, and resource utilization. Current prediction models for postoperative AF are based primarily on Western populations. In this study, we sought to develop a clinical prediction […]
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