Author: Dr Clemens

Uncategorized Published - 13 April, 2017    By - Dr Clemens
Opioid-related hospital stays spike 64%, cost billions in ER, hospital care each year

Overdoses kill 90 people in the United States each day; opioid poisonings Cst more than $20 billion emergency department, hospital care. Hospital stays involving the misuse of prescription painkillers, or the use of illicit opioids like heroin, spiked 64 percent between 2005 and 2014, according to a report by the Agency for Healthcare Research and Quality. […]

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Uncategorized Published - 12 April, 2017    By - Dr Clemens
Advanced Uses of Pulse Oximetry for Monitoring Mechanically Ventilated Patients

Authors: Tusman, Gerardo MD et al Anesthesia & Analgesia: January 2017 – Volume 124 – Issue 1 – p 62–71 Pulse oximetry is an undisputable standard of care in clinical monitoring. It combines a spectrometer to detect hypoxemia with a plethysmograph for the diagnosis, monitoring, and follow-up of cardiovascular diseases. These pulse oximetry capabilities are extremely […]

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Uncategorized Published - 12 April, 2017    By - Dr Clemens
Zika Virus and Patient Blood Management

AUTHORS: Goodnough, Lawrence T. MD et al Anesthesia & Analgesia: January 2017 – Volume 124 – Issue 1 – p 282–289 Sporadic Zika virus infections had only occurred in Africa and Asia until an outbreak in Micronesia (Oceania) in 2007. In 2013 to 2014, several outer Pacific Islands reported local outbreaks. Soon thereafter, the virus was […]

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Uncategorized Published - 12 April, 2017    By - Dr Clemens
Implications of Perioperative Team Setups for Operating Room Management Decisions

AUTHORS: Doll, Dietrich MD, PhD et al Anesthesia & Analgesia: January 2017 – Volume 124 – Issue 1 – p 262–269 BACKGROUND: Team performance has been studied extensively in the perioperative setting, but the managerial impact of interprofessional team performance remains unclear. We hypothesized that the interplay between anesthesiologists and surgeons would affect operating room turnaround […]

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Uncategorized Published - 12 April, 2017    By - Dr Clemens
Intramuscular Fentanyl and Ketorolac Associated with Superior Pain Control After Pediatric Bilateral Myringotomy and Tube Placement Surgery: A Retrospective Cohort Study

AUTHORS: Stricker, Paul A. MD et al Anesthesia & Analgesia: January 2017 – Volume 124 – Issue 1 – p 245–253 BACKGROUND: Bilateral myringotomy and pressure equalization tube insertion (BMT) is the most common surgery in children. Multiple anesthetic techniques for BMT have been proposed, but that which reliably promotes ideal recovery remains unclear. We sought […]

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Uncategorized Published - 12 April, 2017    By - Dr Clemens
Inhibition of Oxidative Stress in Renal Ischemia-Reperfusion Injury

AUTHORS: Choi, Eun Kyung MD, PhD et al Anesthesia & Analgesia: January 2017 – Volume 124 – Issue 1 – p 204–213 BACKGROUND: Superoxide, nitric oxide (NO), and peroxynitrite are important mediators in the pathogenesis of ischemia-reperfusion (I/R) injury. We tested the renoprotective effects of allopurinol (ALP), a xanthine oxidase inhibitor, N-nitro-L-arginine methyl ester (L-NAME), and 5,10,15,20-tetrakis […]

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Uncategorized Published - 11 April, 2017    By - Dr Clemens
Trends in Tramadol: Pharmacology, Metabolism, and Misuse

Authors: Miotto, Karen MD et al Anesthesia & Analgesia: January 2017 – Volume 124 – Issue 1 – p 44–51 Tramadol is a unique analgesic medication, available in variety of formulations, with both monoaminergic reuptake inhibitory and opioid receptor agonist activity increasingly prescribed worldwide as an alternative for high-affinity opioid medication in the treatment of acute […]

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Uncategorized Published - 11 April, 2017    By - Dr Clemens
Association Between Perioperative Hyperglycemia or Glucose Variability and Postoperative Acute Kidney Injury After Liver Transplantation: A Retrospective Observational Study

AUTHORS: Yoo, Seokha MD et al Anesthesia & Analgesia: January 2017 – Volume 124 – Issue 1 – p 35–41 BACKGROUND: Glucose control can be difficult in the intraoperative and immediate postoperative period of liver transplantation. Hyperglycemia and glucose variability have been associated with acute kidney injury (AKI) in critically ill patients. We performed a retrospective […]

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Uncategorized Published - 11 April, 2017    By - Dr Clemens
The Association Between Cyanosis and Thromboelastometry (ROTEM) in Children With Congenital Heart Defects: A Retrospective Cohort Study

AUTHORS: Laskine-Holland, Marie-Laure MD et al Anesthesia & Analgesia: January 2017 – Volume 124 – Issue 1 – p 23–29 BACKGROUND: Children with congenital heart defects (CHD) have quantitative and qualitative differences in coagulation compared with healthy children. Secondary to polycythemia and increased deformability of red blood cells, cyanosis may be an important confounding factor for […]

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Uncategorized Published - 11 April, 2017    By - Dr Clemens
The Association Between Preoperative Hemoglobin A1C and Postoperative Glycemic Variability on 30-Day Major Adverse Outcomes Following Isolated Cardiac Valvular Surgery

AUTHORS: Bardia, Amit MBBS et al Anesthesia & Analgesia: January 2017 – Volume 124 – Issue 1 – p 16–22 BACKGROUND: Preoperative hemoglobin A1c (HbA1c) and postoperative glycemic variability predict major adverse events (MAEs) after coronary artery bypass grafting in a protocolized glycemic control setting. However, the influence of preoperative HbA1c and postoperative glycemic variability in […]

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